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用最大长度序列刺激获得的中潜伏期听觉诱发电位的线性和非线性时间交互成分。

Linear and nonlinear temporal interaction components of mid-latency auditory evoked potentials obtained with maximum length sequence stimulation.

机构信息

Balabee Ltd, 100 Kent Road, Southampton, Hants, SO17 2LH, UK.

出版信息

Exp Brain Res. 2010 Apr;202(1):231-7. doi: 10.1007/s00221-009-2109-6. Epub 2009 Dec 5.

DOI:10.1007/s00221-009-2109-6
PMID:19967341
Abstract

A maximum length sequence (MLS) is a quasi-random sequence of clicks and silences that enables simultaneous recording of linear components and nonlinear temporal interaction components (NLTICs). NLTICs are produced when the stimulation rate is fast enough such that several stimuli occur within the memory length of the system. The present study was designed to characterise the NLTICs of auditory mid-latency responses (MLR). Forty normally hearing subjects (19-45-year-old) were tested at MLS rates between 20 and 120 clicks/s. Linear components could be identified at all rates. The NLTICs of the MLS-MLR were identified in only a few subjects. This suggests two possibilities: (1) there may not be strong nonlinear temporal interactions within the MLR generators; (2) the memory length of the MLR is much shorter than expected from the linear component rates. If so, NLTICs should be obtained at higher rates of stimulation.

摘要

最大长度序列(MLS)是一种准随机的点击和静音序列,可同时记录线性成分和非线性时间相互作用成分(NLTIC)。当刺激率足够快时,会产生 NLTIC,即在系统的记忆长度内发生几个刺激。本研究旨在描述听觉中期潜伏期反应(MLR)的 NLTIC。40 名正常听力受试者(19-45 岁)在 MLS 速率为 20 到 120 次/秒之间进行了测试。在所有速率下都可以识别线性成分。只有少数受试者可以识别 MLS-MLR 的 NLTIC。这表明有两种可能性:(1)MLR 发生器中可能没有强烈的非线性时间相互作用;(2)MLR 的记忆长度比线性成分速率预期的要短得多。如果是这样,应该在更高的刺激速率下获得 NLTIC。

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