Tighe S Q, Turner G A, Merrill S B, Pethybridge R J
Department of Anaesthetics, Royal Naval Hospital Haslar, Cosport, Hampshire.
Anaesthesia. 1991 Jan;46(1):52-6. doi: 10.1111/j.1365-2044.1991.tb09318.x.
Thirty-six servicemen were anaesthetised using the Triservice anaesthetic apparatus. They were allocated randomly into one of two groups, to breathe spontaneously or to receive artificial ventilation, and into subgroups who were given air alone, or air supplemented with 1 or 4 litres/minute of oxygen. A further 12 subjects were studied subsequently using 0.5 litres/minute of added oxygen. Intra-operative blood gases were compared with those of awake premedicated controls. Artificial ventilation was associated with an unchanged arterial oxygen tension with air alone; in the other subgroups arterial oxygen tension was higher than with spontaneous respiration when related to inspired oxygen fraction (p less than 0.05). Air anaesthesia caused significant hypoxaemia with spontaneous ventilation (p less than 0.05), and 50% of the subjects required assisted ventilation. There was also a significant respiratory acidosis (p less than 0.05). Intermittent positive pressure ventilation is the method of choice for field anaesthesia when oxygen is unavailable. Spontaneous respiration must be supplemented with at least 0.5 litres minute of oxygen.
36名军人使用三军通用麻醉设备进行麻醉。他们被随机分为两组,一组自主呼吸,另一组接受人工通气,然后再分为仅吸入空气或吸入补充了每分钟1升或4升氧气的空气的亚组。随后又对另外12名受试者使用每分钟补充0.5升氧气进行了研究。术中血气与清醒的术前用药对照组的血气进行了比较。仅使用空气进行人工通气时,动脉血氧张力不变;在其他亚组中,与吸入氧分数相关时,动脉血氧张力高于自主呼吸时(p<0.05)。空气麻醉在自主通气时导致显著低氧血症(p<0.05),50%的受试者需要辅助通气。还存在显著的呼吸性酸中毒(p<0.05)。当没有氧气时,间歇正压通气是野战麻醉的首选方法。自主呼吸必须补充至少每分钟0.5升氧气。