Cakir Mehmet, Cekiç Osman, Pekel Gökhan, Yilmaz Omer F
Beyoglu Eye Training and Research Hospital, Istanbul, Turkey.
Eur J Ophthalmol. 2010 Mar-Apr;20(2):424-8. doi: 10.1177/112067211002000225.
To identify the etiology, culture results, pars plana vitrectomy results, complications, and visual outcome of exogenous endophthalmitis in children.
Seven eyes of 7 consecutive pediatric patients who were treated and followed up for exogenous endophthalmitis between February 2006 and June 2008 were included in this study. The etiology of endophthalmos was penetrating eye injuries in 4 eyes and intraocular surgery in 3 eyes. Combined pars plana vitrectomy and intravitreal vancomycin plus ceftazidime injection were performed on all 7 eyes. Anterior chamber fluid and vitreous cultures were taken from all eyes. The patient files were inspected retrospectively.
Mean follow-up time was 10.3 months (4-16 months). Mean age of the patients was 8.5 years (3-14 years). At baseline, visual acuity values of the patients were light perception (n=2), hand movements (n=4), and counting fingers from 1 meter (n=1). At final examination, visual acuity improved in 5 eyes, stayed the same in 1 eye, and decreased in 1 eye. Positive culture results were obtained in 3 eyes: alpha hemolytic Streptococcus (n=2) and coagulase-negative Staphylococcus (n=1). Complications seen after vitreoretinal surgery were transient ocular hypertension, emulsification of silicone oil, phthisis bulbi, and secondary retinal detachment.
Early pars plana vitrectomy and intravitreal vancomycin plus ceftazidime injection improved anatomic and functional success in pediatric eyes with exogenous endophthalmitis.
确定儿童外源性眼内炎的病因、培养结果、玻璃体切割术结果、并发症及视力预后。
本研究纳入了2006年2月至2008年6月间连续7例接受外源性眼内炎治疗及随访的儿科患者的7只眼。眼内炎的病因包括4只眼为穿透性眼外伤，3只眼为眼内手术。所有7只眼均行玻璃体切割术联合玻璃体内注射万古霉素加头孢他啶。所有眼均采集前房液和玻璃体进行培养。对患者病历进行回顾性检查。
平均随访时间为10.3个月（4 - 16个月）。患者平均年龄为8.5岁（3 - 14岁）。基线时，患者的视力情况为光感（n = 2）、手动（n = 4）、1米指数（n = 1）。末次检查时，5只眼视力提高，1只眼视力不变，1只眼视力下降。3只眼培养结果为阳性：α溶血性链球菌（n = 2）和凝固酶阴性葡萄球菌（n = 1）。玻璃体视网膜手术后出现的并发症有短暂性眼压升高、硅油乳化、眼球痨和继发性视网膜脱离。
早期玻璃体切割术联合玻璃体内注射万古霉素加头孢他啶可提高儿童外源性眼内炎患眼的解剖和功能预后。
