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[垂体腺瘤的流行病学:瑞士首项研究结果]

[Epidemiology of pituitary adenoma: results of the first Swiss study].

作者信息

Fontana E, Gaillard R

机构信息

Unité de diabétologie et maladie métabolique, Clinique de médecine, HFR-Hôpital cantonal, Chemin des Pensionnats, 1708 Fribourg.

出版信息

Rev Med Suisse. 2009 Oct 28;5(223):2172-4.

Abstract

Epidemiological data concerning pituitary adenomas are very scarce and in some cases reports are even conflicting. This opinion is at present disputed. The aim of this study was, therefore, to evaluate in the urban area of Fribourg, the prevalence of relevant clinical pituitary adenoma. General practitioners, endocrinologists and gynaecologists were questioned concerning any patient within this agglomeration presenting with a pituitary micro- or macro-adenoma. Among the 44 adenomas, we observed 13 non secreting macro-adenomas, 16 micro- and 9 macro-prolactinomas, 4 cases of acromegaly and 2 ACTH-dependant Cushing diseases. In the studied area we found a prevalence of 80.5 pituitary adenomas per 100,000, or 1 case per 1241 corroborating a greater prevalence of pituitary adenomas than previously believed.

摘要

关于垂体腺瘤的流行病学数据非常稀少,在某些情况下,报告甚至相互矛盾。目前这一观点存在争议。因此,本研究的目的是评估弗里堡市区相关临床垂体腺瘤的患病率。我们向全科医生、内分泌学家和妇科医生询问了该聚居区中患有垂体微腺瘤或大腺瘤的任何患者。在44例腺瘤中,我们观察到13例无分泌功能的大腺瘤、16例微腺瘤和9例大泌乳素瘤、4例肢端肥大症和2例促肾上腺皮质激素依赖性库欣病。在研究区域,我们发现垂体腺瘤的患病率为每10万人中有80.5例,即每1241人中有1例,这证实了垂体腺瘤的患病率比以前认为的更高。

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