Department of Cardiac Surgery, Chaim Sheba Medical Center, Tel Hashomer, Israel.
J Thorac Cardiovasc Surg. 2010 Jul;140(1):86-90. doi: 10.1016/j.jtcvs.2009.09.035. Epub 2009 Dec 6.
We sought to compare early and late clinical and echocardiographic outcomes of patients undergoing minimally invasive mitral valve repair by means of the port-access and median sternotomy approaches.
Between 2000 and 2009, 503 patients had mitral valve repair, of whom 143 underwent surgical intervention for isolated posterior leaflet pathology: 61 through port access and 82 through median sternotomy. The port-access group had better preoperative New York Heart Association functional class (P = .007) and a higher rate of elective cases (97% vs 87%, P = .037). Other preoperative characteristics were similar between the groups, including mitral valve pathology and repair techniques.
Operative, bypass, and clamp times were significantly longer in the port-access group. Mean hospital stay was 5.3 +/- 2.5 days in the port-access group versus 5.7 +/- 2.5 days in the median sternotomy group (P = .4). Early postoperative echocardiographic analysis showed that most patients in both groups had none or trivial mitral regurgitation and none of the patients had greater than grade 2 mitral regurgitation. Follow-up extended for up to 100 months (mean, 34 +/- 24 months). New York Heart Association class improved in both groups (P = .394). Freedom from reoperation was 97% and 95% in the port-access and median sternotomy groups, respectively. Late echocardiographic analysis revealed that 82% (49/60) in the port-access group and 91% (73/80) in the median sternotomy group were free from moderate or severe mitral regurgitation (P = .11).
In isolated posterior mitral valve pathology, quality of mitral valve repair with the port-access approach can compare with that with the conventional median sternotomy approach.
我们旨在比较经皮微创二尖瓣修复术(PORT 入路和正中胸骨切开术)的早期和晚期临床及超声心动图结果。
2000 年至 2009 年间,503 例患者接受了二尖瓣修复术,其中 143 例孤立性后叶病变患者接受了外科手术干预:61 例经 PORT 入路,82 例经正中胸骨切开术。PORT 组术前纽约心脏协会功能分级较好(P=0.007),择期手术比例较高(97%比 87%,P=0.037)。两组的其他术前特征相似,包括二尖瓣病变和修复技术。
PORT 组的手术、体外循环和阻断时间明显较长。PORT 组的平均住院时间为 5.3±2.5 天,而正中胸骨切开组为 5.7±2.5 天(P=0.4)。早期术后超声心动图分析显示,两组大多数患者均无或轻度二尖瓣反流,无一例患者出现大于 2 级的二尖瓣反流。随访时间最长达 100 个月(平均 34±24 个月)。两组纽约心脏协会分级均有改善(P=0.394)。PORT 组和正中胸骨切开组的无再次手术生存率分别为 97%和 95%。晚期超声心动图分析显示,PORT 组 82%(49/60)和正中胸骨切开组 91%(73/80)无中度或重度二尖瓣反流(P=0.11)。
在孤立性后二尖瓣病变中,PORT 入路的二尖瓣修复质量可与传统正中胸骨切开术相媲美。