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精索静脉曲张的不孕男性与非精索静脉曲张的不孕男性的睾丸大小差异的患病率。

Prevalence of testicular size discrepancy in infertile men with and without varicoceles.

机构信息

Division of Urology, Warren Alpert Medical School of Brown University, Providence, Rhode Island 02905, USA.

出版信息

Urology. 2010 Mar;75(3):566-8. doi: 10.1016/j.urology.2009.08.084. Epub 2009 Dec 6.

DOI:10.1016/j.urology.2009.08.084
PMID:19969336
Abstract

OBJECTIVES

To compare the frequency of testicular size discrepancy between infertile men with and without varicoceles.

METHODS

The records of adult patients presenting for male infertility evaluations were examined. The testicular volumes and presence or absence of varicocele and varicocele grade were recorded. Testicular size discrepancy was defined as a testicular size difference of at least 4 mL.

RESULTS

Of the 3927 men presenting for male infertility evaluation, 3202 met the inclusion criteria of the study. A total of 705 patients (22%) had testicular size discrepancy and 1105 presented with a varicocele (34%). Testicular size discrepancy was found to be more common in patients with any varicocele than in patients with no varicocele (32% vs 17%; P <.001). In addition, testicular size discrepancy with a smaller left testicle was more common in patients with a left varicocele than in patients with no varicocele (30% vs 13%; P <.001). In patients with a left varicocele, testicular size discrepancy, if present, demonstrated a smaller testicle on the ipsilateral side 89% of the time and on the contralateral side 11% of the time. In contrast, with a right-sided varicocele, if testicular size discrepancy was present, the smaller testicle was located only on the left side.

CONCLUSIONS

Testicular size discrepancy is approximately 2 times more common in infertile men with varicoceles than in men without varicoceles. Testicular size discrepancy with a smaller left testicle is more common than size discrepancy with a smaller right testicle, regardless of the side of the varicocele.

摘要

目的

比较精索静脉曲张患者与非精索静脉曲张患者睾丸大小差异的频率。

方法

检查了前来进行男性不育评估的成年患者的记录。记录了睾丸体积以及精索静脉曲张和精索静脉曲张程度的存在或不存在。睾丸大小差异定义为睾丸大小差异至少为 4 毫升。

结果

在 3927 名前来进行男性不育评估的男性中,有 3202 名符合研究纳入标准。共有 705 名患者(22%)存在睾丸大小差异,1105 名患者存在精索静脉曲张(34%)。与无精索静脉曲张患者相比,任何精索静脉曲张患者中睾丸大小差异更为常见(32%比 17%;P<0.001)。此外,与无精索静脉曲张患者相比,左侧精索静脉曲张患者中睾丸大小差异且左侧睾丸较小更为常见(30%比 13%;P<0.001)。在患有左侧精索静脉曲张的患者中,如果存在睾丸大小差异,则同侧睾丸较小的情况占 89%,对侧睾丸较小的情况占 11%。相比之下,如果存在右侧精索静脉曲张,则睾丸大小差异较小的睾丸仅位于左侧。

结论

与无精索静脉曲张的男性相比,患有精索静脉曲张的男性睾丸大小差异约为 2 倍。与右侧睾丸较小的睾丸大小差异相比,无论精索静脉曲张的侧别如何,左侧睾丸较小的睾丸大小差异更为常见。

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Varicocele-caused progressive damage in bilateral testis and sertoli cell-only syndrome in homolateral testis in rats.
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