新生儿鼻咽部畸胎瘤合并腭裂：2例报告
Nasopharyngeal teratoma associated with cleft palate in newborn: report of 2 cases.
作者信息
He Jie, Wang Yanan, Zhu Hanguang, Qiu Weiliu, He Yue
机构信息
Department of Oral and Maxillofacial Surgery, School of Medicine, Shanghai Jiao-tong University, Shanghai Ninth People's Hospital, Shanghai, China.
出版信息
Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2010 Feb;109(2):211-6. doi: 10.1016/j.tripleo.2009.09.002. Epub 2009 Dec 6.
Teratoma is a true neoplasm that consists of tissues from all 3 embryonic germ layers: ectoderm, mesoderm, and endoderm. Nasopharyngeal teratoma is very rare and accounts for only 2% of all teratomas. We present 2 cases of nasopharyngeal teratomas associated with cleft palate in newborns. The first case was a mushroom-like teratoma arising from the base of the sphenoid bone with cleft soft palate. This case was unique and interesting because no earlier paper has reported a teratoma with such a clinical feature. The second case was a teratoma from the nasal septum of an incomplete cleft palate. The combination of the mass and cleft palate made oral feeding difficult. Complete intraoral resection was performed in both cases. Typical components of true teratoma were identified by microscopic examination after operation. Cleft palate reconstruction was performed before 1 year. Clinical follow-up continues, and no recurrence has been observed to date.
畸胎瘤是一种真正的肿瘤，由外胚层、中胚层和内胚层这三个胚胎胚层的组织构成。鼻咽部畸胎瘤非常罕见，仅占所有畸胎瘤的2%。我们报告2例新生儿鼻咽部畸胎瘤合并腭裂的病例。第一例是起源于蝶骨基部的蘑菇状畸胎瘤，伴有软腭裂。该病例独特且有趣，因为此前没有文献报道过具有这种临床特征的畸胎瘤。第二例是来自不完全腭裂鼻中隔的畸胎瘤。肿物与腭裂并存导致经口喂养困难。两例均进行了完整的口腔内切除。术后通过显微镜检查确定了真性畸胎瘤的典型成分。在1岁前进行了腭裂修复术。临床随访仍在继续，迄今为止未观察到复发。
Zotero 插件