FDA 对儿童抗抑郁药使用和自杀问题发出警告的新闻报道。
News coverage of FDA warnings on pediatric antidepressant use and suicidality.
机构信息
School of Public Health, Yale University, New Haven, Connecticut 06520, USA.
出版信息
Pediatrics. 2010 Jan;125(1):88-95. doi: 10.1542/peds.2009-0792. Epub 2009 Dec 7.
OBJECTIVE
In 2004, after an 18-month investigation, the Food and Drug Administration (FDA) directed pharmaceutical manufacturers to add a black box warning to antidepressants regarding increased risk of suicidality in children. Our objective was to evaluate the quality and content of and overall impression conveyed in news coverage of this issue.
METHODS
We collected all news stories on pediatric antidepressant use and suicidality published in a convenience sample of 10 of the highest-circulation print newspapers in the United States, the 3 major television networks, and a major cable news network in 2003 and 2004 (N = 167). Two researchers coded news articles by using a 9-item instrument.
RESULTS
The quality of news reporting on key health messages included in FDA warnings was mixed. The overwhelming majority of news stories correctly described a risk of suicidality associated with pediatric antidepressant use, as opposed to suicide itself. However, other key health messages highlighted in FDA warnings often were absent from news coverage. News stories were more likely to include anecdotes of children harmed versus children helped by antidepressants, whereas expert sources quoted were more likely to emphasize the benefits of antidepressants over their risks. However, the majority of news stories conveyed neither the overall impression that the risks of pediatric antidepressant use outweighed the benefits nor the impression that the benefits outweighed the risks, and coverage became increasingly neutral over time.
CONCLUSIONS
Inclusion of key health messages in FDA safety warnings was not sufficient to ensure their communication to the public through the lay press.
目的
2004 年，经过为期 18 个月的调查，美国食品和药物管理局（FDA）指示制药商在抗抑郁药的黑框警告中增加儿童自杀风险增加的信息。我们的目的是评估有关这个问题的新闻报道的质量、内容和总体印象。
方法
我们收集了 2003 年和 2004 年在美国 10 家发行量最大的平面报纸、3 大电视网和一家主要有线电视新闻网中方便抽样的所有关于儿科抗抑郁药使用和自杀的新闻报道（N=167）。两名研究人员使用 9 项工具对新闻文章进行编码。
结果
FDA 警告中包含的关键健康信息的新闻报道质量参差不齐。绝大多数新闻报道正确描述了与儿科抗抑郁药使用相关的自杀风险，而不是自杀本身。然而，FDA 警告中强调的其他关键健康信息往往在新闻报道中缺失。新闻报道更倾向于包含儿童因抗抑郁药受到伤害的案例，而不是儿童因抗抑郁药受益的案例，而引用的专家来源更倾向于强调抗抑郁药的益处超过其风险。然而，大多数新闻报道既没有传达儿科抗抑郁药使用的风险超过其益处的总体印象，也没有传达益处超过风险的印象，而且随着时间的推移，报道的态度变得越来越中立。
结论
在 FDA 安全警告中纳入关键健康信息不足以确保通过大众媒体向公众传达这些信息。
Zotero 插件