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针对需要90天隔离期和HIV-1抗体检测的手术供体骨储存的简化方案。

A simplified protocol for banking bone from surgical donors requiring a 90-day quarantine and an HIV-1 antibody test.

作者信息

La Prairie A J, Gross M

机构信息

Victoria General Hospital, Halifax.

出版信息

Can J Surg. 1991 Feb;34(1):41-8.

PMID:1997146
Abstract

The banking of femoral heads from patients who undergo total hip arthroplasty provides a valuable resource for orthopedic surgery. Quality assurance of the banked bone used in clinical procedures requires documented policies for screening, procuring, storing and distributing. Potential donors are screened at the time of donation for malignant disease, possible communicable disease, sepsis and high-risk life-styles. After negative culture results are confirmed and appropriate documentation has been completed, the bone is frozen at -70 degrees C. A quarantine period of 90 days follows. The donor is followed up 90 days or more postoperatively. At that time written consent is obtained for donation of the recovered tissue to the bone bank and for serology testing for human immunodeficiency virus (HIV-1) antibody, hepatitis B surface antigen (HBsAG), hepatitis B core antibody (HBcAb) and syphilis, and the donor is rescreened for contraindications. This protocol meets or exceeds all existing standards. The combination of obtaining consent and serology testing at 90 days streamlines the logistics of banking bone from surgical donors.

摘要

接受全髋关节置换术患者的股骨头储存为骨科手术提供了宝贵资源。临床手术中使用的储存骨的质量保证需要有关于筛选、获取、储存和分发的书面政策。潜在捐赠者在捐赠时要接受恶性疾病、可能的传染病、败血症和高风险生活方式的筛查。在确认培养结果为阴性并完成适当的文件记录后,将骨头在-70摄氏度下冷冻。随后有90天的隔离期。对捐赠者术后进行90天或更长时间的随访。届时要获得捐赠者对将回收组织捐赠给骨库以及进行人类免疫缺陷病毒(HIV-1)抗体、乙肝表面抗原(HBsAG)、乙肝核心抗体(HBcAb)和梅毒血清学检测的书面同意,并对捐赠者重新进行禁忌证筛查。该方案符合或超过所有现行标准。在90天时获取同意和进行血清学检测相结合,简化了来自手术捐赠者的骨储存后勤工作。

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Can J Surg. 1991 Feb;34(1):41-8.
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