口服伤寒活疫苗后人体呼吸道的特异性免疫反应。
Specific immune response in the human respiratory tract following oral immunization with live typhoid vaccine.
作者信息
Forrest B D, LaBrooy J T, Robinson P, Dearlove C E, Shearman D J
机构信息
Department of Medicine, University of Adelaide, Australia.
出版信息
Infect Immun. 1991 Mar;59(3):1206-9. doi: 10.1128/iai.59.3.1206-1209.1991.
Abstract
Specific antibody responses in the lower respiratory tract of human subjects to orally administered Salmonella typhi Ty21a are reported. These responses, predominantly of the immunoglobulin G class, were determined to be a transudate from serum. These results were supported by the similarity in responses to parenteral administration of heat-killed typhoid vaccine. Specific immunoglobulin A antibody was a poor contributor to the respiratory antibody response to either vaccine.
摘要
据报道，人类受试者下呼吸道对口服伤寒沙门氏菌Ty21a的特异性抗体反应。这些反应主要为免疫球蛋白G类，被确定为血清渗出液。对肠外注射热灭活伤寒疫苗的反应相似，支持了这些结果。特异性免疫球蛋白A抗体对两种疫苗的呼吸道抗体反应贡献不大。
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