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非洲野兔身上的痘病毒纤维瘤

Poxvirus fibromas on African hares.

作者信息

Karstad L, Thorsen J, Davies G, Kaminjolo J S

出版信息

J Wildl Dis. 1977 Jul;13(3):245-7. doi: 10.7589/0090-3558-13.3.245.

Abstract

Small dermal tumors were found on three African hares (Lepus capensis) in the Laikipia District, Kenya. Gross and histopathologic studies revealed similarities to the Shope's fibroma of wild rabbits in North America and fibromas of European hares. Histological examination of the African hare fibromas revealed intracytoplasmic inclusion bodies characteristic of poxviruses and poxvirus virions were demonstrated by electron microscopy of ultrathin sections. Attempts to propagate the virus in rabbit skin, embryonated chicken eggs and cell cultures were unsuccessful.

摘要

在肯尼亚莱基皮亚区的三只非洲野兔(南非山兔)身上发现了小的皮肤肿瘤。大体和组织病理学研究显示,这些肿瘤与北美洲野兔的肖普纤维瘤以及欧洲野兔的纤维瘤相似。对非洲野兔纤维瘤进行组织学检查时,发现了痘病毒特有的胞质内包涵体,通过超薄切片的电子显微镜检查证实了痘病毒颗粒的存在。尝试在兔皮肤、鸡胚和细胞培养物中传播该病毒均未成功。

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