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主要组织相容性复合体(MHC)编码的不同鸡品系间B-G同型二聚体和异型二聚体的异质性

MHC coded B-G homodimer and heterodimer heterogeneity among different chicken lines.

作者信息

Kline K, Bacon L D, Dietert R R, Lillehoj H S, Morgan T J, Sanders B G

机构信息

Division of Nutrition, University of Texas, Austin 78712.

出版信息

J Hered. 1991 Jan-Feb;82(1):31-6. doi: 10.1093/jhered/82.1.31.

Abstract

Chicken lines were classified into six distinct groups based on expression of B-G molecules by peripheral red blood cells (RBC). In addition to the previously reported 48 kD subunits of homodimeric B-G molecules, subunits of 60, 40, and possibly 20 kD were detected in certain of the chicken lines. Several of the chicken lines express the previously reported 40 and 44 kD subunits of heterodimeric B-G molecules; however, B21B21 chickens expressed 44 kD subunits only and B5B5 and B13B13 chickens did not express detectable levels of any heterodimeric-related molecules. These studies provide further evidence for the polymorphic nature of the B-G antigens.

摘要

根据外周血红细胞(RBC)中B - G分子的表达情况,鸡品系被分为六个不同的组。除了先前报道的同二聚体B - G分子的48 kD亚基外,在某些鸡品系中还检测到了60、40以及可能的20 kD亚基。几个鸡品系表达了先前报道的异二聚体B - G分子的40和44 kD亚基;然而,B21B21鸡只表达44 kD亚基,而B5B5和B13B13鸡未表达可检测水平的任何异二聚体相关分子。这些研究为B - G抗原的多态性本质提供了进一步的证据。

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