Pfeiffer R F, Wilken K E, Glaeske C S, Hofman R
University of Nebraska Medical Center, Section of Neurology, Omaha 68198-2045.
Nebr Med J. 1991 Jan;76(1):8-10.
Sinemet CR, a controlled release carbidopa/levodopa preparation, was compared to conventional carbidopa/levodopa in a double blind, placebo-controlled trial. Comparable clinical benefits and adverse effects were noted with the two medications. However significantly less frequent dosing was necessary with Sinemet CR.
息宁控释片（Sinemet CR），一种卡比多巴/左旋多巴控释制剂，在一项双盲、安慰剂对照试验中与传统的卡比多巴/左旋多巴进行了比较。两种药物的临床疗效和不良反应相当。然而，息宁控释片的给药频率明显更低。
