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息宁控释片治疗帕金森病

Sinemet CR in Parkinson's disease.

作者信息

Pfeiffer R F, Wilken K E, Glaeske C S, Hofman R

机构信息

University of Nebraska Medical Center, Section of Neurology, Omaha 68198-2045.

出版信息

Nebr Med J. 1991 Jan;76(1):8-10.

PMID:1997878
Abstract

Sinemet CR, a controlled release carbidopa/levodopa preparation, was compared to conventional carbidopa/levodopa in a double blind, placebo-controlled trial. Comparable clinical benefits and adverse effects were noted with the two medications. However significantly less frequent dosing was necessary with Sinemet CR.

摘要

息宁控释片(Sinemet CR),一种卡比多巴/左旋多巴控释制剂,在一项双盲、安慰剂对照试验中与传统的卡比多巴/左旋多巴进行了比较。两种药物的临床疗效和不良反应相当。然而,息宁控释片的给药频率明显更低。

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