Miller R
Proc R Soc Med. 1928 Apr;21(6):997-1004. doi: 10.1177/003591572802100601.
(1) The prevalence of juvenile rheumatism is shown by the incidence of heart disease in 1.5 to 2 per cent. of urban elementary school children. The annual mortality from rheumatic heart disease is probably about 20,000 deaths a year.(2) The age-incidence is due to the three factors of tonsillitis, exposure, and the diminished resistance to infection of childhood. Where these three factors overlap we get the heavy incidence of the infection. The class-incidence shows a rheumatic stratum of society in the upper poorer classes. The disease is therefore not a "poverty disease" strictly so-called; some added factor is also at work.(3) Juvenile rheumatism is clearly an environmental disease, for if the children of the poor are transported from their homes to residential schools they remain free from rheumatic infection. What is the factor at work amongst the poor which produces the disease in their own homes? The evidence that cold damp houses have an important influence in producing juvenile rheumatism is considerable. Overcrowding seems to protect to some extent, owing to the prevention of cold. The environmental causes of the disease must centre largely round the production of tonsillar infection.(4) The organized effort needed to prevent and control juvenile rheumatism consists in increased attention to housing conditions; increased endeavour in early detection by the School Medical Service; increased supervision by hospitals and practitioners of their rheumatic patients; and increased accommodation for prolonged treatment of heart disease.
(1) 青少年风湿病的患病率可通过城市小学1.5%至2%的儿童患心脏病的发病率体现出来。风湿性心脏病的年死亡率可能约为每年2万例。(2) 年龄发病率是由扁桃体炎、接触感染以及儿童抗感染能力下降这三个因素导致的。当这三个因素重叠时,感染发病率就会很高。阶层发病率显示,社会中较贫困的上层阶级存在一个风湿病高发阶层。因此,严格来说,这种疾病并非“贫困疾病”;还有一些其他因素在起作用。(3) 青少年风湿病显然是一种环境疾病,因为如果贫困家庭的孩子被送到寄宿学校,他们就不会受到风湿感染。那么,在贫困家庭中起作用并导致孩子在家中患病的因素是什么呢?有大量证据表明,寒冷潮湿的房屋对青少年风湿病的产生有重要影响。过度拥挤在一定程度上似乎有保护作用,因为它能防止寒冷。这种疾病的环境病因主要围绕扁桃体感染的产生。(4) 预防和控制青少年风湿病所需的有组织的努力包括:更多地关注住房条件;学校医疗服务部门加大早期检测力度;医院和医生加强对风湿病患者的监管;以及增加心脏病长期治疗的床位。