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Role of brain monoamines in the anticonvulsant effect of imipramine in albino rats.

作者信息

Bhattacharya S K, Mukhopadhyay S N, Reddy P K, Das P K

出版信息

Pharmacology. 1976;14(5):428-34. doi: 10.1159/000136625.

Abstract

The role of brain monoamines in the anticonvulsant effect of imipramine was investigated in albino rats, against maximal electroshock-induced seizures, by using drugs with well-defined effects on brain monoamines. The results suggest a definite role for noradrenaline in imipramine anticonvulsant action. Dopamine and 5-hydroxytryptamine do not appear to be involved in this effect of imipramine.

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Role of brain monoamines in the anticonvulsant effect of imipramine in albino rats.
Pharmacology. 1976;14(5):428-34. doi: 10.1159/000136625.

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