Elliott S D
Proc R Soc Med. 1939 May;32(7):747-54. doi: 10.1177/003591573903200712.
Transient streptococcal bacteriaemias are a frequent sequel to dental extractions especially when the mouth is the seat of severe chronic gum infection. Bacteria may also gain admission to the blood-stream in such cases irrespective of operative procedures and probably as the result, in many instances, of minor degrees of gum injury such as is produced by biting on a loose tooth. Acute apical infections do not appear to be especially associated with blood infection of this kind, the focus of infection here apparently being effectively "walled off" by the associated inflammatory reaction.Of the two factors, infection and trauma, involved in the production of these post-operative bacteriaemias, infection appears to be the more important since, when it is marked, very slight degrees of gum injury are sufficient to produce blood-stream invasion. In the complete absence, however, of the type of trauma induced by the "rocking" of a tooth during its removal, extraction may be accomplished without producing a heavy bacterial shower in the blood.Usually these transient bacteriaemias produce no permanent ill-effect, but there is some evidence that, occurring in subjects with abnormal heart valves, they may lead to subacute infective endocarditis. Thirteen cases are reported where the valvular infection appeared to result from a post-operative dental bacteriaemia.Prevention of such bacteriaemias may be achieved by the reduction or elimination of infection and trauma. Complete elimination of the gum infection is difficult although preliminary treatment of the gum margin by some measure such as cauterization may lessen it and lead to a reduction of the post-operative bacterial shower. Similarly, by manipulating an infected tooth as little as possible during its extraction the incidence or degree of blood infection may be decreased.
短暂性链球菌菌血症是拔牙后常见的后遗症,尤其是当口腔存在严重的慢性牙龈感染时。在这种情况下,无论是否进行手术操作,细菌都可能进入血流,而且在许多情况下,可能是由于轻微的牙龈损伤,如咬松动的牙齿所导致的。急性根尖感染似乎与这种血液感染并无特别关联,此处的感染灶显然被相关的炎症反应有效地“隔离”了。
在导致这些术后菌血症的两个因素——感染和创伤中,感染似乎更为重要,因为当感染严重时,非常轻微的牙龈损伤就足以导致细菌侵入血流。然而,如果完全没有拔牙时牙齿“摇晃”所引起的那种创伤,拔牙过程可能不会导致大量细菌进入血液。
通常这些短暂性菌血症不会产生永久性不良影响,但有一些证据表明,在心脏瓣膜异常的患者中发生这种菌血症时,可能会导致亚急性感染性心内膜炎。有13例报告显示瓣膜感染似乎是由术后牙源性菌血症引起的。
通过减少或消除感染和创伤可以预防此类菌血症。虽然通过烧灼等措施对牙龈边缘进行初步治疗可能会减轻牙龈感染并减少术后细菌入血,但完全消除牙龈感染很难。同样,在拔牙过程中尽量减少对感染牙齿的操作,可以降低血液感染的发生率或程度。