一名患有IgA副蛋白血症的患者先后出现坏疽性脓皮病和角层下脓疱性皮肤病。

Pyoderma gangrenosum followed by subcorneal pustular dermatosis in a patient with IgA paraproteinemia.

作者信息

Kohl P K, Hartschuh W, Tilgen W, Frosch P J

机构信息

Universitaets-Hautklinik, Ruprecht-Karls-University Heidelberg, Germany.

出版信息

J Am Acad Dermatol. 1991 Feb;24(2 Pt 2):325-8. doi: 10.1016/0190-9622(91)70043-2.

DOI:10.1016/0190-9622(91)70043-2

PMID:1999540

Abstract

Six months after the occurrence of pyoderma gangrenosum, subcorneal pustular dermatosis developed in a 60-year-old woman. The patient's serum was found to contain an IgA-lambda paraprotein. Although similar cases have been reported, this case is unique in that a distinct episode of pyoderma gangrenosum was followed by subcorneal pustular dermatosis.

摘要

坏疽性脓皮病发生6个月后，一名60岁女性患上了角层下脓疱性皮肤病。发现该患者血清中含有IgA-λ副蛋白。尽管已有类似病例报道，但该病例的独特之处在于，在明显的坏疽性脓皮病发作之后出现了角层下脓疱性皮肤病。