Reeder G S, Nishimura R A, Holmes D R
Division of Cardiovascular Disease, Mayo Clinic, Rochester, Minnesota 55905.
J Am Coll Cardiol. 1991 Mar 15;17(4):909-13. doi: 10.1016/0735-1097(91)90873-8.
Patients enrolled in the Mansfield Scientific Aortic Valvuloplasty Registry were followed up a mean of 7 months after balloon aortic valvuloplasty. Results were compared for patients less than 70, 70 to 79 and greater than or equal to 80 years of age at time of valvuloplasty. As assessed by aortic valve area indexed to body surface area, stenosis was more severe in the older patients and the incidence of congestive heart failure was also greater in those aged greater than or equal to 80 years. The results of valvuloplasty were comparable in all three age groups, and indexed final valve area was not significantly different among the groups. In-hospital mortality ranged from 4.2% to 9.4%, but this and other complications were not significantly different among the groups. Total 7 month mortality was 23%. As performed in this registry study, balloon aortic valvuloplasty produced similar results in older and younger patients, despite initially more severe disease in the older patients.
纳入曼斯菲尔德科学主动脉瓣成形术登记处的患者在球囊主动脉瓣成形术后平均随访7个月。对瓣膜成形术时年龄小于70岁、70至79岁和大于或等于80岁的患者的结果进行了比较。以体表面积校正的主动脉瓣面积评估，老年患者的狭窄更严重，80岁及以上患者的充血性心力衰竭发生率也更高。瓣膜成形术在所有三个年龄组中的结果相当，各组间校正后的最终瓣膜面积无显著差异。住院死亡率在4.2%至9.4%之间，但各组间的这一指标及其他并发症无显著差异。7个月总死亡率为23%。在这项登记研究中，尽管老年患者最初病情更严重，但球囊主动脉瓣成形术在老年和年轻患者中产生了相似的结果。
