Bilello John F, Davis James W, Lemaster Deborah, Townsend Ricard N, Parks Steven N, Sue Lawrence P, Kaups Krista L, Groom Tammi, Egbalieh Babak
Department of Surgery, University of California, Community Regional Medical Center, Fresno, California 93721-1324, USA.
J Trauma. 2011 May;70(5):1038-42. doi: 10.1097/TA.0b013e31819638d0.
Trauma activation for prehospital hypotension in blunt trauma is controversial. Some patients subsequently arrive at the trauma center normotensive, but they can still have life-threatening injuries. Admission base deficit (BD)≤-6 correlates with injury severity, transfusion requirement, and mortality. Can admission BD be used to discriminate those severely injured patients who arrive normotensive but "crump," (i.e., become hypotensive again) in the Emergency Department? The purpose is to determine whether admission BD<-6 discriminates patients at risk for future bouts of unexpected hypotension during evaluation.
Retrospective chart review was performed on all blunt trauma admissions at a Level I trauma center from August 2002 through July 2007. Hypotension was defined as a systolic blood pressure≤90 mm Hg. Patients who were hypotensive in the field but normotensive upon arrival in the emergency department (ED) were included. Age, gender, injury severe score, arterial blood gas analysis, results of focused abdominal sonogram for trauma (FAST), computed tomography, intravenous fluid administration, blood transfusions, and the presence of repeat bouts of hypotension were noted. Patients were stratified by BD≤-6 or ≥-5. Statistical analysis was performed using paired t test, χ, and logistic regression analysis with significance attributed to p<0.05.
During the 5-year period, 231 blunt trauma patients had hypotension in the field with subsequent normotension on admission to the ED. Of these, 189 patients had admission BD data recorded. Patients with a BD≤-6 were significantly more likely to have repeat hypotension (78% vs. 30%, p<0.001). Overall mortality was 13% (24 of 189), but patients with repeat hypotension had greater mortality (24% vs. 5%, p<0.003).
Blunt trauma patients with repeat episodes of hypotension have significantly greater mortality. Patients with transient field hypotension and a BD≤-6 are more than twice as likely to have repeat hypotension (crump). This study reinforces the need for early arterial blood gases and trauma team involvement in the evaluation of these patients. Patients with BD≤-6 should have early invasive monitoring, liberal use of repeat FAST exams, and careful resuscitation before computed tomography scanning. Surgeons should have a low threshold for taking such patients to the operating room.
钝性创伤患者院前低血压的创伤激活存在争议。一些患者随后到达创伤中心时血压正常,但仍可能有危及生命的损伤。入院碱缺失(BD)≤ -6与损伤严重程度、输血需求及死亡率相关。入院BD能否用于鉴别那些到达时血压正常但在急诊科“病情恶化”(即再次出现低血压)的重伤患者?目的是确定入院BD < -6能否鉴别评估期间有未来意外低血压发作风险的患者。
对2002年8月至2007年7月期间在一级创伤中心收治的所有钝性创伤患者进行回顾性病历审查。低血压定义为收缩压≤90 mmHg。纳入在现场低血压但到达急诊科时血压正常的患者。记录年龄、性别、损伤严重程度评分、动脉血气分析、创伤重点腹部超声(FAST)结果、计算机断层扫描、静脉输液、输血情况以及是否再次出现低血压。患者按BD≤ -6或≥ -5分层。采用配对t检验、χ检验及逻辑回归分析进行统计分析,p < 0.05具有统计学意义。
在这5年期间,231例钝性创伤患者在现场出现低血压,随后入院时血压正常。其中,189例患者记录了入院BD数据。BD≤ -6的患者再次出现低血压的可能性显著更高(78%对30%,p < 0.001)。总体死亡率为13%(189例中的24例),但再次出现低血压的患者死亡率更高(24%对5%,p < 0.003)。
反复出现低血压的钝性创伤患者死亡率显著更高。现场短暂低血压且BD≤ -6的患者再次出现低血压(病情恶化)的可能性是前者的两倍多。本研究强化了早期进行动脉血气分析及创伤团队参与评估这些患者的必要性。BD≤ -6的患者应早期进行有创监测,多次使用FAST检查,并在计算机断层扫描前谨慎复苏。外科医生应降低将此类患者送手术室的阈值。