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急诊科的多发伤;我们能否将动脉血气分析与休克分类相关联?

Polytrauma at the Emergency Department; can we relate arterial blood gas analysis to a shock classification?

作者信息

Evers M J, Vaneker M, Biert J

机构信息

Department of Anesthesiology and Nijmegen HEMS, Regional Emergency Healthcare Network, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands.

Department of Surgery, Division of trauma surgery, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands.

出版信息

Eur J Trauma Emerg Surg. 2014 Apr;40(2):169-73. doi: 10.1007/s00068-013-0325-z. Epub 2013 Sep 10.

Abstract

OBJECTIVE

Shock is defined as a change of circulation which results in hypoxia at the tissue level. Lactate and base deficit (BD) are associated with a high risk of multiple organ dysfunction in trauma patients. In this study we evaluated the influence of early recognition of shock in trauma patients.

METHODS

In a retrospective study, relevant data were collected from the Radboud University Nijmegen Medical Centre (RUNMC) database between January 2009 and December 2010. Vital parameters were taken at the accident scene, and patients were divided into four shock classes. Arterial blood gas analysis was performed on arrival in the emergency department. Statistical analysis was performed with SPSS version 17.0. Statistical significance was assumed at p ≤ 0.05.

RESULTS

A total of 255 patients were included. Patients who suffered from prehospital shock, and those who were intubated prior to hospital admittance showed a bad outcome, presenting with a more severe metabolic acidosis, higher ISS and higher mortality. There was a significant difference for bicarbonate and BD between shockclass I + II and shockclass III + IV, respectively 22.7 vs. 19.7 and -3.4 vs. -6.9. Intubated patients had a decreased bicarbonate and BD compared to not intubated patients, respectively 21.81 vs. 23.24 and -5.08 vs. -2.38. Mortality and ISS were higher in patients in shock class III and IV. Significant differences in serum lactate levels were not found.

CONCLUSIONS

Prehospital shock influences patient outcome; outcome of patients is related to initial shock classification. Further validation of our shock classification, however, is necessary.

摘要

目的

休克被定义为导致组织水平缺氧的循环改变。乳酸和碱缺失(BD)与创伤患者发生多器官功能障碍的高风险相关。在本研究中,我们评估了创伤患者休克早期识别的影响。

方法

在一项回顾性研究中,从拉德堡德大学奈梅亨医学中心(RUNMC)数据库收集了2009年1月至2010年12月期间的相关数据。在事故现场获取生命体征参数,并将患者分为四个休克等级。患者到达急诊科后进行动脉血气分析。使用SPSS 17.0版进行统计分析。以p≤0.05为具有统计学意义。

结果

共纳入255例患者。遭受院前休克的患者以及在入院前插管的患者预后较差,表现为更严重的代谢性酸中毒、更高的损伤严重度评分(ISS)和更高的死亡率。休克I + II级和休克III + IV级之间的碳酸氢盐和BD存在显著差异,分别为22.7对19.7以及 -3.4对 -6.9。与未插管患者相比,插管患者的碳酸氢盐和BD降低,分别为21.81对23.24以及 -5.08对 -2.38。休克III级和IV级患者的死亡率和ISS更高。未发现血清乳酸水平存在显著差异。

结论

院前休克影响患者预后;患者的预后与初始休克分级有关。然而,我们的休克分级需要进一步验证。

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