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[谷胱甘肽系统。II. 其他酶、硫醇-二硫键代谢、炎症与免疫、功能]

[Glutathione system. II. Other enzymes, thiol-disulphide metabolism, inflammation and immunity, functions].

作者信息

Kulinskiĭ V I, Kolesnichenko L S

出版信息

Biomed Khim. 2009 Jul-Aug;55(4):365-79.

Abstract

The great significance of glutathione as a redox regulator and the reducing carrier has been established. There is a clear necessity for subdivision of an independent mitochondrial glutathione subsystem. The data on a specificity of glutathione metabolism in different organs are accumulated. The significance of glutathione system for inflammation and immunity has been proved. The investigations of glutathione system for elucidation of pathogenesis of diseases and its diagnostics are used in medicine.

摘要

谷胱甘肽作为一种氧化还原调节剂和还原载体的重要意义已得到确立。明确需要细分出一个独立的线粒体谷胱甘肽子系统。关于不同器官中谷胱甘肽代谢特异性的数据不断积累。谷胱甘肽系统对炎症和免疫的重要性已得到证实。医学上利用对谷胱甘肽系统的研究来阐明疾病的发病机制及其诊断。

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