Department of Dermatology, Karadeniz Technical University, Trabzon, Turkey.
Am J Clin Dermatol. 2010;11(1):59-62. doi: 10.2165/11311120-000000000-00000.
A 55-year-old man presented with multiple, asymptomatic, yellowish papules on his face with a 4-year history, and two non-healing tumoral lesions on his nose with a 7-month history. He was a renal transplant recipient and had been treated with cyclosporine (ciclosporin) for 9 years. A biopsy from the asymptomatic, yellowish papule on the face showed sebaceous gland hyperplasia, and biopsies from the lesions on the nose revealed basal cell carcinomas. The lesions on the nose were excised. Sebaceous gland hyperplasia and skin cancers are among the cutaneous neoplasms observed in renal transplant recipients receiving cyclosporine. To our knowledge, this is the third reported case of the coexistence of basal cell carcinomas and multiple sebaceous gland hyperplasias in a cyclosporine-treated renal transplant recipient.
一位 55 岁男性，因面部多发性无症状黄色丘疹就诊，病史 4 年，鼻部有 2 个非愈合性肿瘤性病变，病史 7 个月。他是一名肾移植受者，已接受环孢素（环孢菌素）治疗 9 年。面部无症状黄色丘疹的活检显示皮脂腺增生，鼻部病变的活检显示基底细胞癌。鼻部病变被切除。肾移植受者接受环孢素治疗后，可观察到皮脂腺增生和皮肤癌等皮肤肿瘤。据我们所知，这是第三例报道的接受环孢素治疗的肾移植受者同时存在基底细胞癌和多发性皮脂腺增生的病例。
