Ryan C B, Kama M, Darcy A, Aleksic E, Mirza T, Chaudhary A, Oelrichs R B, Rogers G D, Crowe S M
Burnet Institute, Melbourne, Australia.
AIDS Res Hum Retroviruses. 2009 Dec;25(12):1355-8. doi: 10.1089/aid.2009.0175.
The HIV epidemic in Fiji remains largely uncharacterized. By February 2009, there were 294 confirmed cases; the majority occurred among the 20- to 39-year old age group and resulted from heterosexual contact. There are currently no published data concerning HIV subtypes in Fiji. In this study, venous blood samples were collected as dried blood spots from 35 HIV-positive individuals in Fiji. HIV-1 subtype was determined for 27 (77%) samples and the presence of four different subtypes, with multiple introductions of two, was demonstrated. Subtype distribution was as follows: 16 (59%) were subtype C, 9 (33%) were subtype B, 1 (4%) was subtype A, and 1 (4%) was subtype G. Phylogenetic analysis showed a clear segregation of the Fijian subtype C isolates and previously published Papua New Guinea subtype C isolates as well as multiple introductions of subtype B. These findings represent the first HIV-1 subtype data from the Fiji Islands.
斐济的艾滋病毒疫情在很大程度上仍未得到充分描述。截至2009年2月，有294例确诊病例；大多数病例发生在20至39岁年龄组，且是由异性接触导致的。目前尚无关于斐济艾滋病毒亚型的已发表数据。在本研究中，从斐济35名艾滋病毒阳性个体采集静脉血样制成干血斑。对27份（77%）样本确定了艾滋病毒-1亚型，并证实存在四种不同亚型，其中两种有多次传入情况。亚型分布如下：16份（59%）为C亚型，9份（33%）为B亚型，1份（4%）为A亚型，1份（4%）为G亚型。系统发育分析显示，斐济C亚型分离株与先前发表的巴布亚新几内亚C亚型分离株明显分开，且B亚型有多次传入。这些发现代表了来自斐济群岛的首批艾滋病毒-1亚型数据。
