Scheenstra Renske J, Muller Sara H, Vincent Andrew, Ackerstaff Annemieke H, Jacobi Irene, Hilgers Frans J M
Department of Head and Neck Oncology and Surgery, The Netherlands Cancer Institute-Antoni van Leeuwenhoek Hospital, Amsterdam, The Netherlands.
Acta Otolaryngol. 2010 Jun;130(6):739-46. doi: 10.3109/00016480903382790.
Both the regularly used heat and moisture exchanger (R-HME) and the HME with both an antimicrobial and hygroscopic element (F-HME) are effective moisture exchangers. The antimicrobial filter of the F-HME acts as a heat exchanger. The external features of the F-HME were experienced as inconvenient, but decreased sputum production was reported as well.
Recently an HME with an integrated antimicrobial filter has become available for use in laryngectomized patients. The purpose of this study was to assess its short-term endotracheal climate changes and feasibility in daily practice.
Endotracheal temperature and humidity were successfully measured in 13 laryngectomized patients (2652 analysed full breaths), during 10 min rest-breathing with the R-HME, with an F-HME and without HME in a randomized sequence. Additionally, a 3 week prospective clinical feasibility trial was conducted in 17 laryngectomized patients.
Both R-HME and F-HME increase endotracheal minimum humidity values (5.8 and 4.7 mgH(2)O/L, respectively; p < 0.0001). Compared with open stoma breathing, in contrast to the R-HME, the F-HME increases both end-inspiratory and end-expiratory temperature values (1.1 degrees C, and 0.6 degrees C, respectively). After the 3-week clinical feasibility trial, one patient dropped out; 11 patients (11/16 = 69%) disliked the larger design of the F-HME and all patients reported less optimal airtight occlusion. Five patients (5/16 = 31%) reported remarkably decreased sputum production.
常用的热湿交换器(R-HME)和兼具抗菌及吸湿功能的热湿交换器(F-HME)都是有效的湿交换器。F-HME的抗菌过滤器可起到热交换器的作用。F-HME的外部特征给人带来不便,但也有报告称其可减少痰液生成。
最近,一种带有集成抗菌过滤器的热湿交换器已可用于喉切除患者。本研究的目的是评估其短期气管内气候的变化情况以及在日常实践中的可行性。
对13例喉切除患者(共分析2652次全呼吸)在静息呼吸10分钟期间,按随机顺序分别使用R-HME、F-HME以及不使用热湿交换器的情况下,成功测量了气管内的温度和湿度。此外,对17例喉切除患者进行了为期3周的前瞻性临床可行性试验。
R-HME和F-HME均可提高气管内的最低湿度值(分别为5.8和4.7 mgH₂O/L;p < 0.0001)。与开放式造口呼吸相比,与R-HME不同,F-HME可提高吸气末和呼气末的温度值(分别为1.1℃和0.6℃)。在为期3周的临床可行性试验后,有1例患者退出;11例患者(11/16 = 69%)不喜欢F-HME较大的设计,所有患者均报告其气密性欠佳。5例患者(5/16 = 31%)报告痰液生成显著减少。