Asai A, Hoffman H J, Matsutani M, Takakura K
Division of Neurosurgery, Hospital for Sick Children, University of Toronto, Canada.
No Shinkei Geka. 1991 Jan;19(1):21-6.
Twelve infants with choroid plexus tumors were reviewed retrospectively. Enlarging head circumference, bulging fontanelle, and vomiting were the major symptoms and signs appearing 2 to 5 weeks (mean = 3.7 weeks) before diagnosis. The average age at diagnosis was 7.7 months. Total removal was performed in 11 patients with choroid plexus papilloma, and partial removal was achieved in 1 patient with a choroid plexus carcinoma. A cerebrospinal fluid (CSF) diversionary shunt was placed temporarily in 6 infants and permanently in 4. Of the two patients not requiring CSF diversionary shunt, 1 needed a subdural-peritoneal shunt postoperatively. Histologically, 11 of 12 tumors were choroid plexus papillomas, and one was a choroid plexus carcinoma. All 12 patients were followed up for 4 months to 11 years (mean = 5.6 years). Eleven of 12 patients were alive at the time of their last check-up. All 11 survivors had normal psychomotor and neurological development. The treatment and outcome of choroid plexus tumors and management of associated hydrocephalus are discussed.
对12例脉络丛肿瘤患儿进行了回顾性研究。头围增大、囟门膨隆和呕吐是诊断前2至5周（平均3.7周）出现的主要症状和体征。诊断时的平均年龄为7.7个月。11例脉络丛乳头状瘤患者进行了全切，1例脉络丛癌患者进行了部分切除。6例婴儿临时置入了脑脊液（CSF）分流管，4例永久置入。在2例不需要脑脊液分流管的患者中，1例术后需要行硬膜下-腹腔分流术。组织学检查显示，12例肿瘤中有11例为脉络丛乳头状瘤，1例为脉络丛癌。12例患者均随访4个月至11年（平均5.6年）。12例患者中有11例在最后一次检查时存活。所有11名幸存者的精神运动和神经发育均正常。本文讨论了脉络丛肿瘤的治疗、预后及相关脑积水的处理。
