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严重低血糖管理:三个欧洲国家的文化相似性、差异性和资源消耗。

Management of severe hypoglycaemia: cultural similarities, differences and resource consumption in three European countries.

机构信息

Novo Nordisk Scandinavia AB, Region Denmark, Arne Jacobsen Alle 15, Copenhagen S, Denmark.

出版信息

J Med Econ. 2009;12(4):269-80. doi: 10.3111/13696990903310501.

DOI:10.3111/13696990903310501
PMID:20001569
Abstract

BACKGROUND

To investigate the characteristics of people with insulin-treated diabetes, who have experienced severe hypoglycaemic events (SHEs), in Germany, Spain or UK.

METHODS

Patients with type 1 (n=319) or insulin-treated type 2 diabetes (n=320) who had experienced ≥ 1 SHE in the preceding year were enrolled. Their median age was 53 years (range, 16-94 years). Data were collected using a questionnaire administered by an experienced interviewer.

RESULTS

The median number of reported SHEs was 2-3 in 12 months. Most events (69%) occurred at home, usually during the day or evening (74%) and most commonly due to insufficient food consumption (45%). In patients whose hypoglycaemia awareness was tested, 68% had normal awareness. Patients requiring emergency healthcare treatment frequently had impaired hypoglycaemia awareness, and developed hypoglycaemic coma more often. Hospital treatment was usually provided in an emergency department (72-94%). The duration of stay was longest in Germany. Following a SHE, patients receiving professional treatment were more likely to: consult their physician, test their blood glucose more often, adjust insulin dose and receive self-management training.

CONCLUSIONS

This survey of diabetes patients aged 16-94 years showed that SHEs represent a substantial burden on national healthcare systems in Germany, UK and Spain. The pattern of occurrence and treatment was similar in all three countries, despite differences in cultures and healthcare systems.

摘要

背景

为了研究在德国、西班牙或英国经历过严重低血糖事件(SHEs)的胰岛素治疗糖尿病患者的特点。

方法

纳入了在过去一年中经历过≥1 次 SHE 的 1 型(n=319)或胰岛素治疗 2 型糖尿病(n=320)患者。他们的中位年龄为 53 岁(范围,16-94 岁)。使用经验丰富的访谈者进行问卷调查收集数据。

结果

中位数报告的 SHE 数为 12 个月内 2-3 次。大多数事件(69%)发生在家庭中,通常在白天或晚上(74%),最常见的原因是食物摄入不足(45%)。在接受低血糖意识测试的患者中,68%的患者意识正常。需要紧急医疗保健治疗的患者经常低血糖意识受损,更容易发生低血糖昏迷。医院治疗通常在急诊科提供(72-94%)。在德国,住院时间最长。SHE 后,接受专业治疗的患者更有可能:咨询医生、更频繁地检测血糖、调整胰岛素剂量和接受自我管理培训。

结论

这项对 16-94 岁糖尿病患者的调查显示,SHEs 对德国、英国和西班牙的国家医疗保健系统构成了重大负担。尽管文化和医疗保健系统存在差异,但在所有三个国家中,发生和治疗模式相似。

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