植入前基因诊断

Preimplantation genetic diagnosis.

作者信息

Petrou Mary

机构信息

Haemoglobinopathy Genetics Centre, Institute of Women's Health, University College London, University College, London, Hospitals NHS Foundation Trust, London, UK.

出版信息

Hemoglobin. 2009;33 Suppl 1:S7-S13. doi: 10.3109/03630260903344838.

DOI:10.3109/03630260903344838

PMID:20001634

Abstract

Couples at risk for having an affected child with homozygous thalassemia or other serious hemoglobin disorder have various options for prevention. The most used in some countries has been prenatal diagnosis with a choice of termination of pregnancy. A more recent addition is preimplantation genetic diagnosis (PGD). In this article, this method is described and reviewed.

摘要

有生育纯合子地中海贫血或其他严重血红蛋白疾病患儿风险的夫妇有多种预防选择。在一些国家最常用的方法是进行产前诊断并可选择终止妊娠。最近增加的一种方法是植入前基因诊断（PGD）。本文将对该方法进行描述和综述。