Centro Integral Oncológico Clara Campal (CIOCC), Madrid, Spain.
World J Surg Oncol. 2009 Dec 14;7:96. doi: 10.1186/1477-7819-7-96.
Surgical resection remains the gold standard for the treatment of localized adenocarcinoma of the extrahepatic bile ducts. Yet, treatment of loco-regional recurrences is not well defined.
We present an unusual case of distal adenocarcinoma of the extrahepatic bile ducts that was treated with surgery and relapsed two years later with a solitary recurrence on the tract of a previous Redon drain. In addition, a review of the literature on management of loco regional relapses is presented.
The ideal management of these patients still remains undefined. Decisions are made based on clinical parameters from retrospective series, such as tumor grade, surgical margins or lymph node involvement. Prospective studies, that include molecular and genetic markers, are needed to improve patient selection and outcomes on this population.
手术切除仍然是治疗肝外胆管局限性腺癌的金标准。然而,局部复发病灶的治疗尚不清楚。
我们报告了一例罕见的肝外胆管远端腺癌病例,该患者接受了手术治疗,两年后在先前 Redon 引流管的路径上出现了单发复发病灶。此外,还对局部复发病灶的治疗文献进行了回顾。
这些患者的理想治疗方法仍未确定。决策是基于回顾性系列中的临床参数做出的,例如肿瘤分级、手术切缘或淋巴结受累。需要进行前瞻性研究,包括分子和遗传标志物,以改善该人群的患者选择和结果。