Department of Radiology, University of Washington, Seattle, WA, USA.
J Cardiovasc Magn Reson. 2009 Dec 15;11(1):53. doi: 10.1186/1532-429X-11-53.
Atherosclerosis is a chronic, progressive, inflammatory disease affecting many vascular beds. Disease progression leads to acute cardiovascular events such as myocardial infarction, stroke and death. The diseased carotid alone is responsible for one third of the 700,000 new or recurrent strokes occurring yearly in the United States. Imaging plays an important role in the management of atherosclerosis, and cardiovascular magnetic resonance (CMR) of the carotid vessel wall is one promising modality in the evaluation of patients with carotid atherosclerotic disease. Advances in carotid vessel wall CMR allow comprehensive assessment of morphology inside the wall, contributing substantial disease-specific information beyond luminal stenosis. Although carotid vessel wall CMR has not been widely used to screen for carotid atherosclerotic disease, many trials support its potential for this indication. This review summarizes the current state of knowledge regarding carotid vessel wall CMR and its potential clinical application for management of carotid atherosclerotic disease.
动脉粥样硬化是一种影响许多血管床的慢性、进行性、炎症性疾病。疾病的进展导致急性心血管事件，如心肌梗死、中风和死亡。仅病变颈动脉就导致了美国每年发生的 70 万例新的或复发的中风中的三分之一。影像学在动脉粥样硬化的管理中起着重要作用，颈动脉血管壁的心血管磁共振（CMR）是评估颈动脉粥样硬化疾病患者的一种很有前途的方式。颈动脉血管壁 CMR 的进步允许对血管壁内部的形态进行全面评估，提供了除管腔狭窄以外的大量特定于疾病的信息。尽管颈动脉血管壁 CMR 尚未广泛用于筛查颈动脉粥样硬化疾病，但许多试验支持其在该适应证中的应用潜力。这篇综述总结了目前关于颈动脉血管壁 CMR 的知识状态及其在颈动脉粥样硬化疾病管理中的潜在临床应用。
