Department of Faculty of Advanced Studies in the Life Sciences, CSJM University, Kanpur, India.
Epidemiol Infect. 2010 Aug;138(8):1096-9. doi: 10.1017/S0950268809991117. Epub 2009 Dec 14.
This study aimed to determine the relationship between hepatitis C virus (HCV) infection and ABO/Rhesus blood groups, age and sex. A total of 20 000 patients who came to donate blood in the blood bank of GSVM Medical College, Kanpur were enrolled in the study. Demographic data recorded for each patient included age, sex and blood group. Blood samples were tested for anti-HCV antibodies and ABO/Rhesus blood group antigen typing was performed. The overall positive rate of anti-HCV was 0.34%. We found that seropositivity for HCV increased with age. Anti-HCV antibodies were detected in 1/765 women (0.13%), compared to 67/19 235 men (0.35%). Seroprevalence of HCV was found to be higher in blood group O individuals (0.42%) and lowest in blood group AB individuals (0.04%). The results of this study demonstrate that that HCV infection may not be related to age and sex but the possible association of blood group antigens with HCV infection cannot be ruled out.
本研究旨在探讨丙型肝炎病毒（HCV）感染与 ABO/Rh 血型、年龄和性别之间的关系。共纳入 20000 名在坎普尔 GSVM 医学院献血的患者。为每位患者记录的人口统计学数据包括年龄、性别和血型。检测血液样本中的抗-HCV 抗体，并进行 ABO/Rh 血型抗原分型。抗-HCV 的总阳性率为 0.34%。我们发现，HCV 血清阳性率随年龄增长而增加。在 765 名女性中检测到抗-HCV 抗体（0.13%），而在 19235 名男性中则有 67 例（0.35%）。O 型血个体的 HCV 血清阳性率（0.42%）最高，AB 型血个体的 HCV 血清阳性率（0.04%）最低。本研究结果表明，HCV 感染可能与年龄和性别无关，但不能排除血型抗原与 HCV 感染之间的可能关联。
