Scientific and Medical Affairs, Sanofi Pasteur, Swiftwater, PA 18370, United States.
Vaccine. 2010 Feb 10;28(6):1451-3. doi: 10.1016/j.vaccine.2009.11.051. Epub 2009 Dec 8.
After a single injection of Typhim Vi (typhoid Vi polysaccharide vaccine), serum antibody concentrations were monitored for 3 years in 37 adults who resided where typhoid fever was not endemic. Anti-Vi antibody concentrations declined progressively during the study, to levels that support the current US recommendation for revaccination every 2 years.
在 37 名居住在非伤寒流行地区的成年人中,单次注射伤寒 Vi 多糖疫苗(Typhim Vi,伤寒 Vi 多糖疫苗)后,监测了 3 年的血清抗体浓度。在研究期间,抗-Vi 抗体浓度逐渐下降,降至支持当前美国每 2 年加强接种一次的建议水平。