Royal Veterinary College, University of London, Hawkshead Lane, Hatfield, Hertfordshire AL9 7TA, UK.
Vet J. 2011 Jan;187(1):42-7. doi: 10.1016/j.tvjl.2009.11.004. Epub 2009 Dec 8.
A case-control study was conducted between December 2005 and August 2006 in London (1) to estimate the strength of association between early ovariohysterectomy (spaying) and urinary incontinence (sphincter mechanism incompetence), (2) to identify other risk factors for incontinence, and (3) to assess any implications of incontinence on the owner-pet relationship. Cases were defined as bitches that developed incontinence after spaying and were treated, and the controls comprised continent spayed bitches. Questionnaires from 202 cases were compared to 168 controls, and analysed using multivariable logistic regression. No significant association between early spaying and incontinence was detected although there was a tendency that early spayed bitches were less likely to be incontinent. Docked bitches were 3.8 times more likely to be incontinent than undocked bitches; bitches weighing over 10 kg were 3.7 times more likely to be incontinent than smaller dogs; and older bitches were more likely to be incontinent (OR=3.1-23.8) than younger animals. Some owners were found to have a negative attitude towards incontinence.
本项病例对照研究于 2005 年 12 月至 2006 年 8 月在伦敦进行，旨在评估早期卵巢子宫切除术（去势）与尿失禁（括约肌机制不全）之间的关联强度，确定其他失禁风险因素，并评估失禁对主宠关系的任何影响。病例组定义为接受去势手术后发生失禁并接受治疗的母犬，对照组为未发生失禁的绝育母犬。对 202 例病例和 168 例对照的问卷进行了比较，并采用多变量逻辑回归进行了分析。尽管早期去势的母犬发生失禁的可能性较低，但未发现早期去势与失禁之间存在显著关联。去尾的母犬发生失禁的可能性是未去尾的母犬的 3.8 倍；体重超过 10 公斤的母犬发生失禁的可能性是体重较小的犬的 3.7 倍；年龄较大的母犬发生失禁的可能性（OR=3.1-23.8）高于年龄较小的犬。研究发现一些主人对失禁存在负面态度。
