Department of Medical Physics in Radiology, Deutsches Krebsforschungszentrum, Im Neuenheimer Feld 280, 69120 Heidelberg, Germany.
J Magn Reson. 2010 Feb;202(2):239-44. doi: 10.1016/j.jmr.2009.11.004. Epub 2009 Nov 18.
Triple-quantum (TQ) filtered sodium MR imaging has been proposed for separation of sodium signal arising from different physiological compartments. In a three-pulse sequence without refocussing pulse, the TQ signal is strongly sensitive to inhomogeneities of the B(0) field. We examine the dependence of the TQ signal intensity on the sequence parameters and propose a modified phase-cycling scheme to improve image quality. A new method for correction of B(0) inhomogeneity artefacts in TQ filtered sodium imaging is presented which requires only two acquisitions to obtain a correction as far as the B(0) inhomogeneity and the pulse widths are not too large. The method was verified in phantom experiments.
三重过滤（TQ）钠磁共振成像技术被提出用于分离来自不同生理隔室的钠信号。在没有重聚焦脉冲的三脉冲序列中，TQ 信号对 B(0)场的不均匀性非常敏感。我们检查了 TQ 信号强度对序列参数的依赖性，并提出了一种改进的相位循环方案来提高图像质量。本文提出了一种新的方法来校正 TQ 过滤钠成像中的 B(0)不均匀伪影，该方法仅需要两次采集即可获得校正，只要 B(0)不均匀性和脉冲宽度不是太大。该方法在体模实验中得到了验证。
