Department of Plastic and Reconstructive Surgery, Hospital of Barmherzige Brüder, Salzburg, Austria.
Surgery. 2011 Feb;149(2):284-90. doi: 10.1016/j.surg.2009.10.040. Epub 2009 Dec 11.
Significant morbidity can result from perineal wounds, particularly if the tissue has been partially devitalized after radiotherapy and extensive resection for cancer or chronic inflammation which may occur in Crohn's disease. Many different types of flaps have been used to improve healing of perineal tissue defects. The purpose of this study was to evaluate the morbidity and outcomes of reconstruction using the local fasciocutaneous infragluteal (FCI) flap.
Fourteen consecutive patients undergoing local FCI flap reconstruction for perineal wounds and defects were included in the study. In 5 female patients, the defect included the dorsal wall of the vagina, which was reconstructed in 1 step. Ten patients underwent operations for anal or low rectal cancer, 3 suffered from Crohn's disease and extensive local fistula formation, and 1 young girl presented with a defect after resection of a perineal synovial sarcoma. Eleven of these patients underwent preoperative chemotherapy and either pre- or intra-operative radiotherapy.
Complete healing of perineal wounds occurred in 13 of the 14 patients. There were 4 flap-related complications, including 3 patients with delayed wound healing and wound dehiscence and 1 patient with partial flap necrosis. The last patient required a second local flap for wound closure. In 2 patients, a second FCI flap was necessary because of a second tumor and a local tumor recurrence. Ambulation and normal mobility were possible after the flap procedure in all patients without restriction of activity. Four patients died during the follow-up period (median, 42.5 months) from tumor metastasis.
Local FCI flap for reconstruction of large perineal defects achieves good wound healing with only moderate morbidity in most patients after extensive resection owing to cancer or Crohn's disease.
会阴伤口会导致显著的发病率,特别是在癌症或慢性炎症(如克罗恩病)广泛切除和放射治疗后组织部分坏死的情况下。为了改善会阴组织缺损的愈合,已经使用了许多不同类型的皮瓣。本研究的目的是评估局部筋膜皮瓣修复会阴组织缺损的发病率和结果。
本研究纳入了 14 例接受局部筋膜皮瓣修复会阴伤口和缺损的连续患者。在 5 名女性患者中,缺损包括阴道背壁,这在 1 步重建中完成。10 例患者因肛门或低位直肠癌症接受手术,3 例患者患有克罗恩病且广泛局部形成瘘管,1 例年轻女孩因会阴滑膜肉瘤切除后出现缺损。这些患者中有 11 例接受了术前化疗,以及术前或术中放疗。
14 例患者中有 13 例会阴伤口完全愈合。有 4 例皮瓣相关并发症,包括 3 例延迟愈合和伤口裂开,1 例部分皮瓣坏死。最后 1 例患者需要第二次局部皮瓣关闭伤口。由于第 2 个肿瘤和局部肿瘤复发,有 2 例患者需要第 2 次筋膜皮瓣。所有患者在皮瓣手术后均可活动,无需限制活动。4 例患者在随访期间(中位随访时间为 42.5 个月)死于肿瘤转移。
对于因癌症或克罗恩病而广泛切除后的大会阴缺损,局部筋膜皮瓣重建可实现良好的伤口愈合,只有大多数患者出现中等发病率。