Center for Plant Molecular Biology (ZMBP), General Genetics, University of Tübingen, Auf der Morgenstelle 28, D-72076 Tübingen, Germany.
Eur J Cell Biol. 2010 Feb-Mar;89(2-3):133-7. doi: 10.1016/j.ejcb.2009.10.014. Epub 2009 Dec 9.
Many different agriculturally important traits, e.g. number and quality of seeds, timing of seed set, fruit ripening, are affected by senescence. Despite the importance of the senescence processes in plants, our knowledge on regulatory mechanisms of senescence is still poor. A central step is a massive reprogramming of the transcriptome, implying an important role of transcription factors. In Arabidopsis 12-16% of all genes are up- or down-regulated. WRKY transcription factors play a central role in controlling leaf senescence in Arabidopsis. One important member of this family, WRKY53, is tightly regulated by different unexpected mechanisms and is a convergence node between senescence and biotic and abiotic stress responses.
许多农业上重要的性状，例如种子的数量和质量、种子的形成时间、果实的成熟，都受到衰老的影响。尽管衰老过程在植物中很重要，但我们对衰老调控机制的了解仍然很差。一个关键步骤是转录组的大规模重编程，这意味着转录因子起着重要的作用。在拟南芥中，有 12-16%的基因被上调或下调。WRKY 转录因子在拟南芥的叶片衰老中起着核心作用。这个家族的一个重要成员 WRKY53 受到不同意外机制的严格调控，是衰老与生物和非生物胁迫反应之间的汇聚节点。
