发作间期双相障碍的睡眠、疾病进程和并发症状。
Sleep, illness course, and concurrent symptoms in inter-episode bipolar disorder.
机构信息
Department of Psychology, University of California, Berkeley, CA 94720-1650, USA.
出版信息
J Behav Ther Exp Psychiatry. 2010 Jun;41(2):145-9. doi: 10.1016/j.jbtep.2009.11.007. Epub 2009 Dec 1.
Abstract
We investigated associations between sleep, illness course, and concurrent symptoms in 21 participants with bipolar disorder who were inter-episode. Sleep was assessed using a week-long diary. Illness course and symptoms were assessed via validated semi-structured interviews. Lower and more variable sleep efficiency and more variable total wake time were associated with more lifetime depressive episodes. Variability in falling asleep time was positively correlated with concurrent depressive symptoms. Sleep efficiency was positively correlated with concurrent manic symptoms. These findings suggest that inter-episode sleep disturbance is associated with illness course and that sleep may be an important intervention target in bipolar disorder.
摘要
我们调查了 21 名处于缓解期的双相情感障碍患者的睡眠、疾病进程和并发症状之间的关联。使用为期一周的日记评估睡眠。通过经过验证的半结构化访谈评估疾病过程和症状。较低且更可变的睡眠效率和更多变的总清醒时间与更多的终生抑郁发作有关。入睡时间的可变性与并发抑郁症状呈正相关。睡眠效率与并发躁狂症状呈正相关。这些发现表明缓解期睡眠障碍与疾病进程有关，睡眠可能是双相情感障碍的一个重要干预靶点。
相似文献
1
Sleep, illness course, and concurrent symptoms in inter-episode bipolar disorder.
J Behav Ther Exp Psychiatry. 2010 Jun;41(2):145-9. doi: 10.1016/j.jbtep.2009.11.007. Epub 2009 Dec 1.
2
Clinical significance of mobile health assessed sleep duration and variability in bipolar disorder.
J Psychiatr Res. 2016 Oct;81:152-9. doi: 10.1016/j.jpsychires.2016.07.008. Epub 2016 Jul 9.
3
Study of the different sleep disturbances during the prodromal phase of depression and mania in bipolar disorders.
Bipolar Disord. 2024 Aug;26(5):454-467. doi: 10.1111/bdi.13429. Epub 2024 Apr 23.
4
Sleep architecture as correlate and predictor of symptoms and impairment in inter-episode bipolar disorder: taking on the challenge of medication effects.
J Sleep Res. 2010 Dec;19(4):516-24. doi: 10.1111/j.1365-2869.2010.00826.x.
5
Sleep functioning in relation to mood, function, and quality of life at entry to the Systematic Treatment Enhancement Program for Bipolar Disorder (STEP-BD).
J Affect Disord. 2009 Apr;114(1-3):41-9. doi: 10.1016/j.jad.2008.06.028. Epub 2008 Aug 15.
6
Co-occurrence of disturbed sleep and appetite loss differentiates between unipolar and bipolar depressive episodes.
Prog Neuropsychopharmacol Biol Psychiatry. 2002 Oct;26(6):1041-5. doi: 10.1016/s0278-5846(02)00213-0.
7
Evaluating sleep in bipolar disorder: comparison between actigraphy, polysomnography, and sleep diary.
Bipolar Disord. 2012 Dec;14(8):870-9. doi: 10.1111/bdi.12021.
8
Residual depressive symptoms, sleep disturbance and perceived cognitive impairment as determinants of functioning in patients with bipolar disorder.
J Affect Disord. 2017 Mar 1;210:280-286. doi: 10.1016/j.jad.2016.12.054. Epub 2017 Jan 3.
9
Correlates and prognostic relevance of sleep irregularity in inter-episode bipolar disorder.
Compr Psychiatry. 2016 Aug;69:155-62. doi: 10.1016/j.comppsych.2016.05.016. Epub 2016 May 30.
10
Long term course of bipolar I disorder in India: using retrospective life chart method.
J Affect Disord. 2015 Mar 1;173:255-60. doi: 10.1016/j.jad.2014.10.056. Epub 2014 Nov 13.
引用本文的文献
1
Interaction of daytime and nighttime light exposure on objective sleep quality in patients with bipolar disorder: a cross-sectional analysis of the APPLE cohort.
Transl Psychiatry. 2025 Aug 18;15(1):291. doi: 10.1038/s41398-025-03549-3.
2
Factors Associated With Sleep Disturbance Amongst Youth With Bipolar Disorder.
J Can Acad Child Adolesc Psychiatry. 2022 Nov;31(4):165-175. Epub 2022 Nov 1.
3
Developing "MinDag" - an app to capture symptom variation and illness mechanisms in bipolar disorder.
Front Med Technol. 2022 Jul 22;4:910533. doi: 10.3389/fmedt.2022.910533. eCollection 2022.
4
Associations between comorbid anxiety and sleep disturbance in people with bipolar disorder: Findings from actigraphy and subjective sleep measures.
J Affect Disord. 2022 Jul 15;309:165-171. doi: 10.1016/j.jad.2022.04.065. Epub 2022 Apr 12.
5
Misperception of sleep in bipolar disorder: an exploratory study using questionnaire versus actigraphy.
Int J Bipolar Disord. 2020 Nov 20;8(1):34. doi: 10.1186/s40345-020-00198-x.
6
Neuropsychology of Bipolar Disorder.
Curr Top Behav Neurosci. 2021;48:239-253. doi: 10.1007/7854_2020_148.
7
Using Chronobiological Phenotypes to Address Heterogeneity in Bipolar Disorder.
Mol Neuropsychiatry. 2020 Apr;5(Suppl 1):72-84. doi: 10.1159/000506636. Epub 2020 Feb 20.
8
Pharmacological Manipulation of the Circadian Clock: A Possible Approach to the Management of Bipolar Disorder.
CNS Drugs. 2019 Oct;33(10):981-999. doi: 10.1007/s40263-019-00673-9.
9
The association between mood state and chronobiological characteristics in bipolar I disorder: a naturalistic, variable cluster analysis-based study.
Int J Bipolar Disord. 2018 Feb 19;6(1):5. doi: 10.1186/s40345-017-0113-5.
10
Insomnia as a Precipitating Factor in New Onset Mental Illness: a Systematic Review of Recent Findings.
Curr Psychiatry Rep. 2017 Aug;19(8):44. doi: 10.1007/s11920-017-0802-x.
本文引用的文献
1
The effect of mood on sleep onset latency and REM sleep in interepisode bipolar disorder.
J Abnorm Psychol. 2009 Aug;118(3):448-58. doi: 10.1037/a0016605.
2
Hypersomnia across mood disorders: a review and synthesis.
Sleep Med Rev. 2009 Aug;13(4):275-85. doi: 10.1016/j.smrv.2008.09.001. Epub 2009 Mar 9.
3
Sleep and circadian rhythms in bipolar disorder: seeking synchrony, harmony, and regulation.
Am J Psychiatry. 2008 Jul;165(7):820-9. doi: 10.1176/appi.ajp.2008.08010098. Epub 2008 Jun 2.
4
Sleep disturbance in bipolar disorder: therapeutic implications.
Am J Psychiatry. 2008 Jul;165(7):830-43. doi: 10.1176/appi.ajp.2008.08010077. Epub 2008 May 15.
5
Cognitive behavioral therapy for insomnia enhances depression outcome in patients with comorbid major depressive disorder and insomnia.
Sleep. 2008 Apr;31(4):489-95. doi: 10.1093/sleep/31.4.489.
6
The impairment of pediatric bipolar sleep: hypotheses regarding a core defect and phenotype-specific sleep disturbances.
J Affect Disord. 2008 Jun;108(3):199-206. doi: 10.1016/j.jad.2007.10.007. Epub 2007 Nov 14.
7
The human emotional brain without sleep--a prefrontal amygdala disconnect.
Curr Biol. 2007 Oct 23;17(20):R877-8. doi: 10.1016/j.cub.2007.08.007.
8
Psychosocial treatments for bipolar depression: a 1-year randomized trial from the Systematic Treatment Enhancement Program.
Arch Gen Psychiatry. 2007 Apr;64(4):419-26. doi: 10.1001/archpsyc.64.4.419.
9
Effectiveness of adjunctive antidepressant treatment for bipolar depression.
N Engl J Med. 2007 Apr 26;356(17):1711-22. doi: 10.1056/NEJMoa064135. Epub 2007 Mar 28.
10
Psychological and behavioral treatment of insomnia:update of the recent evidence (1998-2004).
Sleep. 2006 Nov;29(11):1398-414. doi: 10.1093/sleep/29.11.1398.
Zotero 插件