Department of Psychology, University of California, Berkeley, Berkeley, CA 94720, USA.
Bipolar Disord. 2012 Dec;14(8):870-9. doi: 10.1111/bdi.12021.
Bipolar disorder is an illness characterized by sleep and circadian disturbance, and monitoring sleep in this population may signal an impending mood change. Actigraphy is an important clinical and research tool for examining sleep, but has not yet been systematically compared to polysomnography or sleep diary in bipolar disorder. The present study compares actigraphy, polysomnography, and sleep diary estimates of five standard sleep parameters in individuals with bipolar disorder and matched controls across two nights of assessment.
Twenty-seven individuals who met diagnostic criteria for bipolar disorder type I or II and were currently between mood episodes, along with 27 matched controls with no history of psychopathology or sleep disturbance, underwent two nights of research laboratory monitoring. Sleep was estimated via polysomnography, actigraphy, and sleep diary.
Over the 108 nights available for comparison, sleep parameter estimates from actigraphy and polysomnography were highly correlated and did not differ between the two groups or across the two nights for sleep onset latency, wake after sleep onset, number of awakenings, total sleep time, or sleep efficiency percentage. The medium wake threshold algorithm in the actigraphy software was the most concordant with polysomnography and diaries across the five sleep parameters. Concordance between actigraphy, polysomnography, and sleep diary was largely independent of insomnia presence and medication use.
Actigraphy is a valid tool for estimating sleep length and fragmentation in bipolar disorder.
双相情感障碍是一种以睡眠和昼夜节律紊乱为特征的疾病，监测该人群的睡眠情况可能预示着情绪即将发生变化。活动记录仪是检查睡眠的重要临床和研究工具，但尚未在双相情感障碍患者中与多导睡眠图或睡眠日记进行系统比较。本研究比较了活动记录仪、多导睡眠图和睡眠日记在 2 天评估中对 27 名符合双相情感障碍 I 型或 II 型诊断标准且目前处于情绪发作之间的个体以及 27 名无精神病史或睡眠障碍史的匹配对照者的 5 项标准睡眠参数的估计值。
27 名符合双相情感障碍 I 型或 II 型诊断标准且目前处于情绪发作之间的个体以及 27 名无精神病史或睡眠障碍史的匹配对照者，进行了 2 个晚上的研究实验室监测。通过多导睡眠图、活动记录仪和睡眠日记来估计睡眠。
在可用于比较的 108 个晚上中，活动记录仪和多导睡眠图的睡眠参数估计值高度相关，两组之间或两个晚上之间的睡眠潜伏期、睡眠后觉醒、觉醒次数、总睡眠时间或睡眠效率百分比均无差异。活动记录仪软件中的中唤醒阈值算法在五个睡眠参数中与多导睡眠图和日记最一致。活动记录仪、多导睡眠图和睡眠日记之间的一致性在很大程度上独立于失眠的存在和药物的使用。
活动记录仪是估计双相情感障碍中睡眠长度和碎片化的有效工具。
