Wales Institute of Cognitive Neuroscience, School of Psychology, Cardiff University, Park Place, Cardiff CF103AT, UK.
Appetite. 2010 Feb;54(1):225-8. doi: 10.1016/j.appet.2009.12.002. Epub 2009 Dec 11.
This study focused on genetic and behavioural aspects of one important component of the motivation to eat - how appetitive arousal is elicited through the presentation of food-associated stimuli. Individuals with Prader-Willi syndrome, a genetic disorder associated with hyperphagia, and control participants completed a computerised response task in the presence of motivational stimuli. In controls, appetitive arousal was specific to particular stimuli. In contrast, individuals with PWS showed a non-specific pattern of arousal. Over-activation of the anticipatory motivation system may be one consequence of the genetic disorder in PWS.
本研究关注的是进食动机的一个重要组成部分的遗传和行为方面 - 即食物相关刺激如何引起食欲唤起。患有 Prader-Willi 综合征（一种与贪食症相关的遗传疾病）的个体和对照组参与者在有动机刺激的情况下完成了计算机反应任务。在对照组中，食欲唤起是特定于特定刺激的。相比之下，患有 PWS 的个体表现出非特异性的唤醒模式。预期动机系统的过度激活可能是 PWS 遗传障碍的后果之一。
