Schulz-Wendtland R, Bauer M, Teufel G, Ladner H A
Abteilung Gynäkologische Radiologie, Universität Freiburg.
Strahlenther Onkol. 1991 Feb;167(2):82-8.
From 1976 to 1985 151 recurrent carcinomas of the uterine cervix were diagnosed and in 118 cases they have been treated at the Gynaecological Centre of the University of Freiburg. The recurrences were divided according to the localisation scheme of Munnell and Bonney. 55 patients (47%) received radiotherapy, 22 (19%) surgery, 12 (10%) combined therapy of surgery and radiotherapy and 13 women (11%) chemotherapy or hormone therapy. 16 patients (13%) received a different type of therapy. We found most of the recurrences three or four years after the primary therapy. There was no correlation between the point of time of diagnosis of the recurrences and the prognosis. The distribution of the histology was no parameter for the OAS. The operative procedure demonstrates better results than the radiotherapy at recurrences in the centre of the pelvis--but there is no significance. The radiotherapy achieves significant better results than the operative treatment when we have large recurrences in the whole pelvis. If there is an answer of the tumour to the therapy, the OAS gets better--in these cases we should use, in spite of the risk of more side effects, the whole therapeutic range.
1976年至1985年间，共诊断出151例子宫颈复发性癌，其中118例在弗莱堡大学妇科中心接受了治疗。复发情况根据Munnell和Bonney的定位方案进行划分。55例患者（47%）接受了放射治疗，22例（19%）接受了手术治疗，12例（10%）接受了手术与放射治疗的联合治疗，13例女性（11%）接受了化疗或激素治疗。16例患者（13%）接受了其他类型的治疗。我们发现大多数复发发生在初次治疗后的三到四年。复发的诊断时间与预后之间没有相关性。组织学分布不是总缓解率（OAS）的参数。在盆腔中央复发时，手术治疗的效果优于放射治疗——但差异无统计学意义。当整个盆腔出现大面积复发时，放射治疗的效果明显优于手术治疗。如果肿瘤对治疗有反应，总缓解率会提高——在这些情况下，尽管存在更多副作用的风险，我们仍应采用全部治疗手段。
