Int J Cardiol. 2011 Jul 15;150(2):e73-6. doi: 10.1016/j.ijcard.2009.11.012. Epub 2009 Dec 14.
The coexistence of Brugada Syndrome and resting vasospastic angina resulting in cardiac arrest is rare. We describe a 64 year-old man presenting with cardiac arrest and vasospastic angina with diagnostic criteria of symptomatic Brugada Syndrome. Recognition of the coexistence of these potentially fatal conditions has important therapeutic implications when using calcium channel antagonists and may shed light on the mechanisms of coronary spasm. A common pathogenesis, such as a common underlying channelopathy, may explain its coexistence with Brugada Syndrome.
Brugada 综合征与静息性血管痉挛性心绞痛并存导致心搏骤停较为罕见。我们描述了一位 64 岁男性,因心搏骤停和血管痉挛性心绞痛就诊,具有 Brugada 综合征的症状性诊断标准。当使用钙通道拮抗剂时,认识到这些潜在致命情况的并存具有重要的治疗意义,并可能阐明冠状动脉痉挛的机制。共同的发病机制,如共同的潜在通道病,可能解释其与 Brugada 综合征并存的原因。