Cole Kendra L, Wang Ernest E, Aronwald Richard M
Department of Emergency Medicine, Northwestern University, Chicago, Illinois 60611, USA.
J Emerg Med. 2012 Aug;43(2):e89-91. doi: 10.1016/j.jemermed.2009.09.020. Epub 2009 Dec 14.
Patients with migraine headaches are frequently prescribed topiramate to treat their condition.
We present a case of bilateral acute angle-closure glaucoma occurring 2 days after topiramate therapy was increased for symptoms related to migraine.
Acute angle-closure glaucoma secondary to topiramate is an uncommon but serious adverse reaction that may result in severe morbidity such as permanent visual loss if not recognized in a timely manner. Treatment differs from primary acute angle-closure glaucoma in that discontinuation of topiramate is necessary for the glaucoma to resolve.
偏头痛患者经常被开托吡酯来治疗他们的病情。
我们报告一例双侧急性闭角型青光眼，该病例发生在因偏头痛相关症状增加托吡酯治疗量2天后。
托吡酯继发的急性闭角型青光眼是一种罕见但严重的不良反应，如果不能及时识别，可能导致严重的发病情况，如永久性视力丧失。其治疗与原发性急性闭角型青光眼不同，因为必须停用托吡酯青光眼才能缓解。
