Cell. 2009 Dec 11;139(6):1029-31. doi: 10.1016/j.cell.2009.11.038.
Reversible epigenetic changes that alter gene expression are a characteristic of many cancers and other diseases. Biotech companies are taking note and are starting to develop new drugs to reverse such pathogenic "epimutations."
可逆的表观遗传改变会改变基因表达,这是许多癌症和其他疾病的一个特征。生物技术公司已经注意到这一点,并开始开发新的药物来逆转这种致病的“表观突变”。