女性与内在的男性作斗争。
Females battle to suppress their inner male.
机构信息
Murdoch Children's Research Institute, Melbourne, Victoria 3052, Australia.
出版信息
Cell. 2009 Dec 11;139(6):1051-3. doi: 10.1016/j.cell.2009.11.036.
PMID:20005799
Abstract
Conventional wisdom holds that the ovary and testis are terminally differentiated organs in adult mammals. However, Uhlenhaut et al. (2009) now report that deletion of a single gene, Foxl2, is sufficient to induce transdifferentiation of ovary into testis in adult mice, suggesting that testicular development is actively repressed throughout the life of females.
摘要
传统观点认为，哺乳动物的卵巢和睾丸是成年期终末分化的器官。然而，Uhlenhaut 等人（2009 年）现在报告称，删除单个基因 Foxl2 足以诱导成年小鼠的卵巢向睾丸转化，这表明睾丸发育在雌性的整个生命周期中都受到积极抑制。
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