Department of Chemical Physiology, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA.
Mol Cell. 2009 Dec 11;36(5):730-1. doi: 10.1016/j.molcel.2009.11.023.
In this issue of Molecular Cell, Foit et al. (2009) probe cellular protein folding using a split beta-lactamase approach for evolving protein stability in the absence of any requirement for function.
本期《分子细胞》中,Foit 等人(2009 年)采用分裂β-内酰胺酶的方法研究细胞内蛋白质折叠,在无需任何功能要求的情况下研究蛋白质稳定性的进化。