Massachusetts General Hospital Cancer Center, Harvard Medical School, Charlestown, MA 02129, USA.
Mol Cell. 2009 Dec 11;36(5):734-5. doi: 10.1016/j.molcel.2009.11.026.
In this issue of Molecular Cell, Navadgi-Patil and Burgers show that the budding yeast Mec1 kinase is activated by DNA damage through two distinct Ddc1-mediated mechanisms during G1 and G2 phases of the cell cycle.
在本期《分子细胞》中，Navadgi-Patil 和 Burgers 表明，在细胞周期的 G1 和 G2 期，芽殖酵母 Mec1 激酶通过两种不同的 Ddc1 介导的机制被 DNA 损伤激活。
