Kosma Etolou 11, Thessaloniki, Greece.
J Dent. 2010 Mar;38(3):173-81. doi: 10.1016/j.jdent.2009.12.002. Epub 2010 Jan 6.
The purpose of this study was to investigate the possible influence of age on the longevity of tooth supported fixed prosthetic restorations, using a systematic review process.
To identify relevant papers an electronic search was made using various databases (MEDLINE via Pubmed, EMBASE, The Cochrane Register of RCTs, the database of abstracts of Reviews of Effects-DARE), augmented by hand searching of key prosthodontic journals (International Journal of Prosthodontics, Journal of Prosthetic Dentistry and Journal of Prosthodontics) and reference cross-check.
Assessment and selection of studies identified were conducted in a two phase procedure, by two independent reviewers utilizing specific inclusion and exclusion criteria. The minimum mean follow-up time was set at 5 years.
The initial database search yielded 513 relevant titles. After the subsequent filtering process, 22 articles were selected for full-text analysis, finally resulting in 11 studies that met the inclusion criteria. All studies were classified as category C according to the strength of evidence. Meta-analysis was not possible due to the non-uniformity of the data available. The final studies were presented with conflicting results. The majority of the final studies did not report a statistically significant effect of age on fixed prostheses survival, whilst only one study reported poorer prognosis for elderly patients, and two studies reported poorer prognosis for middle-aged patients.
The results of this systematic review showed that increased age of patients should not be considered as a risk factor for the survival of fixed prostheses. Although the majority of studies did not show any effect of age on the survival of fixed prostheses, there was some evidence that middle-aged patients may present with higher failure rates.
本研究旨在通过系统评价的方法，探究年龄对牙支持式固定修复体寿命的可能影响。
为了确定相关文献，我们使用多种数据库（通过 Pubmed 检索 MEDLINE、EMBASE、Cochrane 对照试验注册中心、疗效摘要数据库-DARE）进行了电子检索，同时还对手头的主要修复学杂志（《国际口腔修复学杂志》、《修复牙科学杂志》和《修复学杂志》）进行了检索，并进行了参考文献交叉核对。
两位独立评审员采用特定的纳入和排除标准，分两个阶段进行评估和选择研究。最小平均随访时间设定为 5 年。
最初的数据库搜索产生了 513 个相关标题。经过后续的筛选过程，有 22 篇文章被选入全文分析，最终有 11 项研究符合纳入标准。所有研究根据证据强度均被归类为 C 类。由于可用数据的不一致性，无法进行荟萃分析。最终的研究结果存在争议。大多数最终研究报告表明，年龄对固定修复体存活率没有统计学上的显著影响，只有一项研究报告称老年患者的预后较差，两项研究报告称中年患者的预后较差。
本系统评价的结果表明，患者年龄的增加不应被视为固定修复体存活率的一个危险因素。尽管大多数研究并未显示年龄对固定修复体存活率有任何影响，但有一些证据表明中年患者的失败率可能更高。
