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妊娠中期蛛网膜下腔感觉阻滞的扩散与布比卡因的高压。

Spread of subarachnoid sensory block with hyperbaric bupivacaine in second trimester of pregnancy.

机构信息

Department of Anesthesiology and Pain Medicine, School of Medicine, Ewha Womans University Mokdong Hospital, Seoul, Korea.

出版信息

J Clin Anesth. 2009 Nov;21(7):482-5. doi: 10.1016/j.jclinane.2008.12.018.

Abstract

STUDY OBJECTIVE

To compare the spread of subarachnoid sensory block with hyperbaric bupivacaine in second trimester pregnant and non-pregnant women.

DESIGN

Prospective study.

SETTING

University teaching hospital.

PATIENTS

44 ASA physical status I and II women patients, 22 of whom were in their second trimester of pregnancy undergoing cervical cerclage, and 22 non-pregnant women scheduled for perianal surgery.

INTERVENTIONS

The extent of sensory block and hemodynamic changes were assessed.

MEASUREMENTS

Number of dermatomes blocked was determined by testing for pinprick; systolic blood pressure (SBP), diastolic blood pressure (DBP), and heart rate (HR) were measured at 3, 5, 10, 15, 30 and 60 minutes.

MAIN RESULTS

Maximal sensory block was higher in the second trimester of the pregnant group by three dermatomes than the non-pregnant group. There were no statistically significant differences in SBP, DBP, or HR changes between the groups.

CONCLUSION

Pregnant women in the second trimester exhibit enhanced spread of spinal analgesia with hyperbaric bupivacaine more so than non-pregnant women.

摘要

研究目的

比较蛛网膜下腔感觉阻滞在妊娠中期和非妊娠妇女中应用重比重布比卡因的扩散情况。

设计

前瞻性研究。

地点

大学教学医院。

患者

44 例 ASA 体格Ⅰ和Ⅱ级的女性患者,其中 22 例为妊娠中期行宫颈环扎术的孕妇,22 例为计划行肛门周围手术的非孕妇。

干预措施

评估感觉阻滞的范围和血液动力学变化。

测量

通过针刺测试确定感觉阻滞的皮节数;测量收缩压(SBP)、舒张压(DBP)和心率(HR),分别在 3、5、10、15、30 和 60 分钟进行。

主要结果

妊娠组的最大感觉阻滞比非妊娠组高三个皮节。两组之间 SBP、DBP 或 HR 变化无统计学显著差异。

结论

妊娠中期的孕妇与非孕妇相比,重比重布比卡因的脊髓镇痛扩散增强。

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