Section of Vascular Surgery, University of Michigan, Ann Arbor, MI, USA.
Semin Vasc Surg. 2009 Dec;22(4):245-51. doi: 10.1053/j.semvascsurg.2009.10.007.
While endoluminal procedures are now commonly done for symptomatic peripheral arterial disease, vein bypass remains the gold standard for revascularization. Lower extremity vein bypass procedure success is dependent on patient factors, surgical judgment and technique, including use of medications. Cardioprotective medications have proven efficacy to decrease morbidity and mortality, but their use to improve graft patency is less well known. We review the up to date use of medications with known vascular effects that may promote graft success, as well as decrease cardiovascular events in this high risk patient group.
虽然腔内治疗现在常用于治疗有症状的外周动脉疾病，但静脉旁路仍然是血运重建的金标准。下肢静脉旁路手术的成功取决于患者因素、手术判断和技术，包括药物的使用。心脏保护药物已被证明能降低发病率和死亡率，但它们在改善移植物通畅性方面的作用知之甚少。我们回顾了具有已知血管作用的药物的最新使用情况，这些药物可能有助于提高移植物的成功率，并降低这一高危患者群体的心血管事件风险。
