Kesarwani Siddharth, Murthy Ramesh, Vemuganti Geeta K
Departments of Pediatric Ophthalmology, Strabismus, and Neuroophthalmology, Miriam Hyman Children's Eye Care Centre, LV Prasad Eye Institute, Patia, Bhubaneswar, India.
J AAPOS. 2009 Dec;13(6):618-20. doi: 10.1016/j.jaapos.2009.09.010.
Congenital fibrovascular pupillary membrane, rare in newborns, poses challenges for the ophthalmic surgeon. Predicting its clinical course is difficult, as is removing the membrane surgically without inducing a cataract. We describe a 22-day-old girl who presented with a pupillary membrane causing progressive decrease in the size of the dilated pupil, necessitating removal at 4 months of age. Histopathology demonstrated tissue of embryonic muscle origin, suggesting that the membrane was more likely a remnant of fetal iris than of fetal vasculature. The smooth muscle or fibroblastic elements in the tissue explains progressive contracture of the membrane.
先天性纤维血管性瞳孔膜在新生儿中罕见，给眼科医生带来挑战。预测其临床病程很困难，手术切除该膜而不诱发白内障也很困难。我们描述了一名22日龄女孩，她出现瞳孔膜导致散瞳后瞳孔大小逐渐减小，因此在4个月大时需要进行切除。组织病理学显示为胚胎肌肉起源的组织，提示该膜更可能是胎儿虹膜的残余而非胎儿血管的残余。组织中的平滑肌或成纤维细胞成分解释了该膜的进行性挛缩。
