Department of Pediatrics, Ankara University Medical School, Dikimevi, Ankara, Turkey.
J Trop Pediatr. 2010 Aug;56(4):260-2. doi: 10.1093/tropej/fmp110. Epub 2009 Dec 9.
Kawasaki disease (KD) is the leading cause of acquired heart disease in childhood in the developed countries. The objective of this study is to describe the clinical and epidemiological characteristics of children with KD in Turkey.
The medical records of 24 patients treated for KD between January 1994 and June 2009 at Ankara University Medical School, Turkey were reviewed.
The male-to-female ratio was 1.4 : 1. The median age at diagnosis was 2 years (range: 6.5 months to 11 years). Conjunctivitis and changes in the lips and oral cavity were seen in 21/24 (87.5%), cervical lymphadenopathy 17/24 (70.8%), polymorphous rash 16/24 (66.7%) and peripheral changes in 12/24 (50%). Coronary artery abnormality (CAA) was observed in 8/24 (33.3%) cases. CAA was seen in both the complete and incomplete groups with similar frequency (31.3% vs. 37.5%, respectively).
KD must be kept in mind in the differential diagnosis of infants with prolonged fever.
川崎病（KD）是发达国家儿童获得性心脏病的主要病因。本研究旨在描述土耳其儿童 KD 的临床和流行病学特征。
回顾了 1994 年 1 月至 2009 年 6 月间在土耳其安卡拉大学医学院治疗的 24 例 KD 患儿的病历。
男女比例为 1.4:1。中位诊断年龄为 2 岁（范围：6.5 个月至 11 岁）。24 例（87.5%）患儿出现结膜炎和唇舌改变，17 例（70.8%）出现颈部淋巴结肿大，16 例（66.7%）出现多形性皮疹，12 例（50%）出现外周改变。8/24（33.3%）例存在冠状动脉异常（CAA）。完全型和不完全型 KD 患儿的 CAA 发生率相似（31.3%与 37.5%）。
对于发热时间较长的婴儿，应注意鉴别诊断 KD。
